Evidence map›Paper›PMID 38095272›Full record

ArticleTopics in stroke rehabilitation2024

Reduced oxygen desaturation in the vastus lateralis of chronic stroke survivors during graded muscle contractions.

Allison S Hyngstrom, Jennifer N Nguyen, Spencer A Murphy, Stephanie C Raab, Brian D Schmit, David D Gutterman, Matthew J Durand

Open access · greenAbstract read
In one paragraph

Article in Topics in stroke rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Allison S HyngstromDepartment of Physical Therapy, Marquette University, Milwaukee, WI, USA.
Jennifer N NguyenDepartment of Physical Medicine and Rehabilitation, Medical College of Wisconsin, Milwaukee, WI, USA.
Spencer A MurphyDepartment of Physical Therapy, Marquette University, Milwaukee, WI, USA.
Stephanie C RaabDepartment of Physical Therapy, Marquette University, Milwaukee, WI, USA.
Brian D SchmitDepartment of Biomedical Engineering, Marquette University and the Medical College of Wisconsin, Milwaukee, WI, USA.
David D GuttermanDepartment of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Matthew J DurandDepartment of Physical Medicine and Rehabilitation, Medical College of Wisconsin, Milwaukee, WI, USA.
Marquette University · USMedical College of Wisconsin · US

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
Institutional Career Development CoreKL2TR001438 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI WIDLANSKY, MICHAEL E · 2015 to 2024
$2.9M
Ischemic Conditioning and Improved Motor Function Post StrokeR01HD099340 · NICHD · MARQUETTE UNIVERSITY · PI DURAND, MATTHEW, HYNGSTROM, ALLISON SUZANNE · 2019 to 2023
$2.1M
NCATS NIH HHS KL2 TR001438NCATS NIH HHS UL1 TR001436NICHD NIH HHS R01 HD099340
6 · The paper itself

Abstract

backgroundFew studies have examined changes in skeletal muscle physiology post-stroke. This study examined changes in tissue oxygen saturation (StO

objectivesWe hypothesized that tissue oxygen desaturation (ΔStO

methodsTen chronic stroke survivors (>6 months post-stroke) with lower extremity muscle weakness and 10 age-matched controls completed this prospective cohort study. Maximum voluntary contractions (MVCs) of the knee extensor muscles were assessed with a Biodex dynamometer and StO

resultsIn the paretic leg of the stroke survivors little change in StO

conclusionsThese results indicate that oxygen desaturation in response to isometric muscle contractions is impaired in both the paretic and non-paretic leg muscle of stroke survivors compared to age-matched controls, and these differences are independent of differences in muscle strength.

Indexed as

Quadriceps MuscleStrokeAgedChronic DiseaseFemaleHumansIsometric ContractionMaleMiddle AgedMuscle ContractionOxygen SaturationParesisProspective StudiesSpectroscopy, Near-InfraredSurvivorsexercisemuscle functionmuscle Strengtheningoxygen kineticsPhysical inactivityStroke

Identifiers

PMID38095272
PMCPMC11129930
OpenAlexW4389742594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.