ArticleAllergy2024
Glatiramer acetate induces mast cell degranulation via MRGPRX2, implications for local and systemic adverse reactions.
Shaswati Chaki, Aetas Amponnawarat, Brett Levenstein, Yvonne Hui, Carole Oskeritzian, Hydar Ali
Open access · bronzeAbstract readLetter
In one paragraphArticle in Allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
6 authors at 2 institutions in 2 countries.
Shaswati ChakiDepartment of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Aetas AmponnawaratDepartment of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.ORCID 0009-0005-4989-2761 Brett LevensteinDepartment of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Yvonne HuiDepartment of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South California, USA.
Carole OskeritzianDepartment of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South California, USA.ORCID 0000-0003-1380-9186 Hydar AliDepartment of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-9190-1960 Translational Therapeutics (United States) · USUniversity of South Carolina · US
Funding
Targeting early ceramide elevation in pre-symptomatic eczemaP20GM103641 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ENOS, REILLY, NAGARKATTI, PRAKASH S · 2012 to 2023
$20.7MRoles of novel MRGPRX2/MrgprB2 signaling in mast cells on host defense and InflammationR01AI149487 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Hydar Ali · 2020 to 2026
$3.9MRole of a novel human mast cell G protein coupled receptor in Allergy and InflammationR01AI124182 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Hydar Ali · 2016 to 2026
$2.5MNovel Roles of GRK2 and beta-arrestin2 on mast cell-mediated allergy and InflammationR01AI143185 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ALI, HYDAR · 2020 to 2024
$2.4MNIAID NIH HHS R01 AI124182NIAID NIH HHS R01 AI143185NIAID NIH HHS R01 AI149487NIGMS NIH HHS P20 GM103641NIGMS NIH HHS P20GM103641NIH HHS R01-AI124182NIH HHS R01-AI143185NIH HHS R01-AI149487
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
AnaphylaxisDrug HypersensitivityCell DegranulationGlatiramer AcetateHumansMast CellsNerve Tissue ProteinsReceptors, G-Protein-CoupledReceptors, NeuropeptideGlatiramer AcetateMRGPRX2 protein, humanNerve Tissue ProteinsReceptors, G-Protein-CoupledReceptors, Neuropeptide
Identifiers
PMID38095027
PMCPMC10922971
OpenAlexW4389741993
What OpenQuestion holds
Textmetadata
LicenceTDM
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