Evidence map›Paper›PMID 38094871›Full record

Observational studyJournal of diabetes research2023

Coagulation Function and Type 2 Diabetic Kidney Disease: A Real-World Observational Study.

Meng-Chao Liu, Wen-Quan Niu, Yue-Fen Wang, Yuan Meng, Gui-Min Zheng, Zhen Cai, Cun Shen, Xiang-Gang Zhu, Meng-di Wang, Jia-Lin Li and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of diabetes research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Meng-Chao LiuDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-7330-5935
Wen-Quan NiuCenter for Evidence-Based Medicine, Capital Institute of Pediatrics, Beijing, China.
Yue-Fen WangDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yuan MengDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Gui-Min ZhengDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Zhen CaiDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Cun ShenDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Xiang-Gang ZhuDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Meng-di WangDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Jia-Lin LiDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Wen-Jing ZhaoDepartment of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-3264-5976
Yao-Xian WangHenan University of Chinese Medicine, China.ORCID https://orcid.org/0000-0002-1927-9529

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Type 2 diabetic kidney disease (DKD), a chronic microvascular complication of diabetes, may exhibit a complex interrelation with coagulation function. This study is aimed at elucidating the association between coagulation function and DKD. Methods: This was a real-world observational study conducted in Beijing, involving 2,703 participants. All patients with diabetes were classified into two groups, viz., DKD and non-DKD groups. Effect magnitudes are denoted as odds ratios (OR) with a 95% confidence interval (CI). To mitigate potential bias in group comparisons, we employed propensity score matching (PSM). Results: After adjusting for variables such as age, gender, systolic blood pressure (SBP), hemoglobin A1c (HbA1c), triglyceride (TG), c-reactive protein (CRP), platelet (PLT), and serum albumin (sALB), it was discerned that fibrinogen (FIB) (OR, 95% CI, Conclusions: Our findings suggest that elevated levels of FIB and FDP serve as potential risk indicators for DKD, and coagulation function may play an important role in the occurrence and development of DKD.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesC-Reactive ProteinFibrinogenHumansRisk FactorsC-Reactive ProteinFibrinogen

Identifiers

PMID38094871
PMCPMC10719035

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.