Evidence map›Paper›PMID 38094647›Full record

ArticleMovement disorders clinical practice2023

An Empirical Comparison of Commonly Used Universal Rating Scales for Dystonia.

Deniz Boz, Gamze Kilic-Berkmen, Joel S Perlmutter, Scott A Norris, Laura J Wright, Christine Klein, Tobias Bäumer, Sebastian Löns, Jeanne S Feuerstein, Abhimanyu Mahajan and 8 more

Open access · greenAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 2 countries.

Deniz BozCollege of Arts & Sciences Georgia State University Atlanta Georgia USA.
Gamze Kilic-BerkmenDepartment of Neurology Emory University School of Medicine Atlanta Georgia USA.
Joel S PerlmutterDepartment of Neurology, Radiology, Neuroscience, Physical Therapy and Occupational Therapy Washington University School of Medicine St Louis Missouri USA.
Scott A NorrisDepartment of Neurology and Radiology Washington University St Louis Missouri USA.
Laura J WrightDepartment of Neurology at Washington University at St Louis St Louis Missouri USA.
Christine KleinInstitute of Neurogenetics University of Lübeck Lübeck Germany.
Tobias BäumerInstitute of Neurogenetics University of Lübeck Lübeck Germany.
Sebastian LönsInstitute of Neurogenetics University of Lübeck Lübeck Germany.
Jeanne S FeuersteinDepartment of Neurology University of Colorado Aurora Colorado USA.
Abhimanyu MahajanRush Parkinson's disease and Movement disorders program, Department of Neurological Sciences Chicago Illinois USA.
Aparna Wagle-ShuklaFixel Institute for Neurological Disease, University of Florida Department of Neurology University of Florida Gainesville Florida USA.
Irene MalatyFixel Institute for Neurological Disease, University of Florida Department of Neurology University of Florida Gainesville Florida USA.
Mark S LeDouxDepartment of Psychology University of Memphis, Memphis, TN, USA; Veracity Neuroscience LLC Memphis Tennessee USA.
William OndoDepartment of Neurology, Methodist Neurological Institute Houston TX and Weill Cornell Medical School New York New York USA.
Alexander PantelyatDepartment of Neurology Johns Hopkins University School of Medicine Baltimore Maryland USA.
Samuel FrankBeth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts USA.
Rachel Saunders-PullmanDepartment of Neurology Icahn School of Medicine at Mount Sinai, and Mount Sinai Beth Israel New York New York USA.
H A JinnahDepartment of Neurology Emory University School of Medicine Atlanta Georgia USA.
University of Lübeck · DEWashington University in St. Louis · USEmory University · USCornell University · USGeorgia State University · USHarvard University · USJohns Hopkins University · USMount Sinai Beth Israel · USRush University · USUniversity of Colorado Denver · USUniversity of Florida · USUniversity of Florida Health · USUniversity of Memphis · US

Funding

Dystonia Coalition- Pilot ProjectU54NS116025 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2019 to 2023
$7.1M
The Role of Striatal Cholinergic Interneurons in DystoniaR01NS124789 · NINDS · WASHINGTON UNIVERSITY · PI Scott Allen Norris · 2022 to 2026
$3.0M
Dystonia CoalitionU54TR001456 · NCATS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2015 to 2016
$2.5M
RES FACIL CONST: NEUROSCIENCE: LANGUAGE, COGNITION &BEHAVIOR, PAIN, DEPRESSIONC06RR020092 · NCRR · WASHINGTON UNIVERSITY · PI STANLEY, SAMUEL · 2004 to 2004
$1.6M
NCATS NIH HHS U54 TR001456NCRR NIH HHS C06 RR020092NINDS NIH HHS R01 NS124789NINDS NIH HHS U54 NS116025
6 · The paper itself

Abstract

Background: There are several widely used clinical rating scales for documenting the severity and distribution of various types of dystonia. Objectives: The goal of this study was to evaluate the performance of the most commonly used scales in a large group of adults with the most common types of isolated dystonia. Methods: Global Dystonia Rating Scale (GDRS) and the Burke-Fahn-Marsden Dystonia Rating Scale (BFM) scores were obtained for 3067 participants. Most had focal or segmental dystonia, with smaller numbers of multifocal or generalized dystonia. These scales were also compared for 209 adults with cervical dystonia that had Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) scores and 210 adults with blepharospasm that had Blepharospasm Severity Scale (BSRS) scores. Results: There were strong correlations between the GDRS and BFM total scores ( Conclusions: The BFM is more widely used than the GDRS, but these results suggest the GDRS may be preferable for focal and segmental dystonias. The overabundance of very low scores for both scales highlights challenges associated with discriminating very mild dystonia from other abnormal movements or variants of normal behavior.

Indexed as

blepharospasmBlepharospasm rating scaleBurke‐Fahn‐Marsden dystonia rating scalecervical dystoniaglobal dystonia rating scalelaryngeal dystoniarating scalesegmental dystoniaToronto Western torticollis rating scale

Identifiers

PMID38094647
PMCPMC10715345
OpenAlexW4387907836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.