Evidence map›Paper›PMID 38094620›Full record

ArticleJAACAP open2023

A Randomized Clinical Trial of Technology-Enhanced Family-Focused Therapy for Youth in the Early Stages of Mood Disorders.

David J Miklowitz, Marc J Weintraub, Megan C Ichinose, Danielle M Denenny, Patricia D Walshaw, Catherine A Wilkerson, Samantha J Frey, Georga M Morgan-Fleming, Robin D Brown, John A Merranko and 1 more

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAACAP open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03913013 (Technology-Enhanced Family-Focused Treatment for Adolescents at High Risk for Mood Disorders), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03913013 phase1 / phase2completednot on this map

Technology-Enhanced Family-Focused Treatment for Adolescents at High Risk for Mood Disorders

TypeinterventionalSponsorUniversity of California, Los AngelesRan2018 to 2021Enrolled65ConditionsMood Disorders, Bipolar Disorder, Major DepressionArmsFamily-Focused Treatment with MCC App
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
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  9. Editors' Best of 2023.JAACAP open · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

David J MiklowitzSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at University of California, Los Angeles, California.ORCID 0000-0002-9647-6147
Marc J WeintraubSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at University of California, Los Angeles, California.ORCID 0000-0001-8724-120X
Megan C IchinoseSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at University of California, Los Angeles, California.ORCID 0000-0003-0745-0795
Danielle M DenennySemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at University of California, Los Angeles, California.ORCID 0000-0001-6707-677X
Patricia D WalshawSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at University of California, Los Angeles, California.ORCID 0000-0002-4080-595X
Catherine A WilkersonSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at University of California, Los Angeles, California.ORCID 0000-0003-1664-4129
Samantha J FreySemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at University of California, Los Angeles, California.ORCID 0000-0003-1438-2401
Georga M Morgan-FlemingSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at University of California, Los Angeles, California.
Robin D BrownSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at University of California, Los Angeles, California.
John A MerrankoUniversity of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.ORCID 0000-0002-0637-0059
Armen C ArevianChorus Innovations, Inc., Long Beach, California.
University of California, Los Angeles · USMaterial Innovations (United States) · USUniversity of Pittsburgh Medical Center · US

Funding

Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy TrialR01MH123575 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E, MIKLOWITZ, DAVID JAY · 2020 to 2023
$5.4M
Neurodevelopment and Psychosis in the 22q11.2 Copy Number VariantsR37MH085953 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CARRIE E BEARDEN · 2023 to 2026
$2.9M
Technology-Enhanced Family-Focused Treatment for Adolescents at High Risk for Mood DisordersR34MH117200 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AREVIAN, ARMEN C, MIKLOWITZ, DAVID JAY · 2018 to 2020
$933k
App-Enhanced CBT for Adolescents at High Risk for Severe Mood DisordersK23MH124015 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WEINTRAUB, MARC JOSHUA · 2021 to 2024
$779k
NIMH NIH HHS K23 MH124015NIMH NIH HHS R01 MH123575NIMH NIH HHS R34 MH117200NIMH NIH HHS R37 MH085953
6 · The paper itself

Abstract

Objective: Family-focused therapy (FFT) is associated with enhanced outcomes in youth with bipolar and depressive disorders, but has not been evaluated in conjunction with mobile health tools. In symptomatic adolescents whose parents had histories of mood disorders, we examined whether the effects of telehealth-based FFT were augmented by mobile health apps that emphasized mood tracking and family coping skills. Method: Participants (aged 13-19 years) had active mood symptoms and a parent with major depressive or bipolar disorder. Participants received 12 sessions in 18 weeks of telehealth FFT, with random assignment to (1) a mobile app (MyCoachConnect, MCC) that enabled mood tracking, reviews of session content, and text reminders to practice mood management and family communication skills (FFT-MCC); or (2) a mobile app that enabled mood tracking only (FFT-Track). Independent evaluators assessed youth every 9 weeks over 6 months on depressive symptoms (primary outcome), anxiety, and psychosocial functioning. Results: Participants (N = 65; mean age 15.8 ± 1.6 years) significantly improved in depressive symptoms over 6 months ( Conclusion: Youth in the early stages of mood disorder may benefit from FFT enhanced by mobile health apps. Collaborations between researchers and information technologists on mobile app design and user experience may lead to increases in engagement among adolescents. Clinical trial registration information: Technology Enhanced Family Treatment; https://clinicaltrials.gov/; NCT03913013.

Indexed as

bipolar disorderdepressionmobile appsmobile healthtelehealth

Identifiers

PMID38094620
PMCPMC10718175
OpenAlexW4366977640

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.