Evidence map›Paper›PMID 38094013›Full record

ArticleChinese herbal medicines2023

Isolation, characterization and modulatory potentials of

Kehinde Oluseun Sodeinde, Akinwunmi Oluwaseun Adeoye, Adedeji Adesipo, Adebayo A Adeniyi, John Adeolu Falode, Tajudeen Olabisi Obafemi, Samuel Olalekan Olusanya, Linette Twigge, Jeanet Conradie, Timothy O Mosaku

Open access · goldAbstract read
In one paragraph

Article in Chinese herbal medicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Haplotype-Phased Chromosome-Level Genome Assembly ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Kehinde Oluseun SodeindeDepartment of Chemistry, Federal University Oye-Ekiti, Ekiti State 371104, Nigeria.
Akinwunmi Oluwaseun AdeoyeBiomembrane, Toxicology and Drug Discovery Unit, Department of Biochemistry, Federal University Oye-Ekiti, Ekiti State 371104, Nigeria.
Adedeji AdesipoDepartment of Chemistry, Federal University Oye-Ekiti, Ekiti State 371104, Nigeria.
Adebayo A AdeniyiDepartment of Chemistry, Federal University Oye-Ekiti, Ekiti State 371104, Nigeria.
John Adeolu FalodeBiomembrane, Toxicology and Drug Discovery Unit, Department of Biochemistry, Federal University Oye-Ekiti, Ekiti State 371104, Nigeria.
Tajudeen Olabisi ObafemiDepartment of Biochemistry, Afe Babalola University, Ado-Ekiti, Ekiti State 360001, Nigeria.
Samuel Olalekan OlusanyaDepartment of Chemistry, Federal University Oye-Ekiti, Ekiti State 371104, Nigeria.
Linette TwiggeDepartment of Chemistry, University of Free State, Bloemfontein 9301, South Africa.
Jeanet ConradieDepartment of Chemistry, University of Free State, Bloemfontein 9301, South Africa.
Timothy O MosakuDepartment of Civil Engineering, Covenant University, Ogun State 112104, Nigeria.
Federal University Oye Ekiti · NGUniversity of the Free State · ZAAfe Babalola University · NGCovenant University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Secondary metabolites and polyphenolic compounds from medicinal plants have been demonstrated to have multiple biological functions with promising research and development prospects. This study examined the effect of Methods: The compounds were isolated by vacuum liquid chromatography. Mitochondrial swelling was assessed as changes in absorbance under succinate-energized conditions. Results: Conclusion: Reduction in the activity of calcium ATPase and the expression of Caspase-3 and -9 were observed, suggesting that they could play a role in protecting physicochemical properties of membrane bilayers from free radical-induced severe cellular damage and be useful in the management of diseases where much apoptosis occurs.

Indexed as

Anchomanes difformis (Blume) Engl.ergosterolmitochondrial membranemodulationtransition porexylopic acidβ-stigmasterol

Identifiers

PMID38094013
PMCPMC10715878
OpenAlexW4385237422

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.