Evidence map›Paper›PMID 38093979›Full record

ArticleFrontiers in medicine2023

Comparison of two RT-qPCR methods targeting BK polyomavirus microRNAs in kidney transplant recipients.

Kenza Zoubir, Véronique Descamps, Aurélien Aubry, Francois Helle, Catherine Francois, Sandrine Castelain, Etienne Brochot, Baptiste Demey

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kenza ZoubirLaboratoire de Virologie, Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France.
Véronique DescampsLaboratoire de Virologie, Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France.
Aurélien AubryLaboratoire de Virologie, Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France.
Francois HelleUR UPJV 4294, Agents Infectieux, Résistance et Chimiothérapie (AGIR), Centre Universitaire de Recherche en Santé, Université de Picardie Jules Verne, Amiens, France.
Catherine FrancoisLaboratoire de Virologie, Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France.
Sandrine CastelainLaboratoire de Virologie, Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France.
Etienne BrochotLaboratoire de Virologie, Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France.
Baptiste DemeyLaboratoire de Virologie, Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France.
Centre Hospitalier Universitaire Amiens-Picardie · FRAgents infectieux, résistance et chimiothérapie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: BK polyomavirus replication leads to progressive tubulointerstitial nephritis and ureteral stenosis, with a considerable risk of subsequent graft failure in kidney transplant recipients. Since specific antiviral therapies are lacking, new tools are required to enhance the biological monitoring of the infection. Viral microRNAs are promising new biomarkers, but the performance of RT-qPCR methods limits the clinical application and the validation of a standard method for quantification. Methods: We compared Results: Cycle threshold values were constantly higher with Conclusion: Overall,

Indexed as

biomarkerBK polyomaviruscomparisonkidney transplantationmicroRNART-qPCR

Identifiers

PMID38093979
PMCPMC10716916
OpenAlexW4389093918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.