Evidence map›Paper›PMID 38093975›Full record

ArticleFrontiers in medicine2023

Repurposing of Rutan showed effective treatment for COVID-19 disease.

Shavkat I Salikhov, Ibrokhim Y Abdurakhmonov, Yuliya I Oshchepkova, Jamolitdin F Ziyavitdinov, Nodir Sh Berdiev, Haji Akber Aisa, Jingshan Shen, Yechun Xu, H Eric Xu, Xiangrui Jiang and 8 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05862883 (Studying the Efficiency of the Natural Preparation Rutan in Children in the Treatment of COVID-19, Acute Respiratory Viral Infections, and Developing Treatment Protocols), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05862883 phase2completednot on this map

Studying the Efficiency of the Natural Preparation Rutan in Children in the Treatment of COVID-19, Acute Respiratory Viral Infections, and Developing Treatment Protocols

TypeinterventionalSponsorResearch Institute of Virology, Ministry of Health of the Republic of UzbekistanRan2021 to 2022Enrolled301ConditionsCOVID-19 Respiratory InfectionArmsRutan 25 mg, Control group
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Current issues in molecular biology · 2026
    Article
  2. Sumac Polyphenols as Pan-Herpesvirus Inhibitors.International journal of molecular sciences · 2025
    Article
  3. Review
  4. Computational andFrontiers in pharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Shavkat I SalikhovA.S. Sadykov Institute of Bioorganic Chemistry (UzAS), Tashkent, Uzbekistan.
Ibrokhim Y AbdurakhmonovCenter of Genomics and Bioinformatics, Academy of Sciences of Uzbekistan, Tashkent, Uzbekistan.
Yuliya I OshchepkovaA.S. Sadykov Institute of Bioorganic Chemistry (UzAS), Tashkent, Uzbekistan.
Jamolitdin F ZiyavitdinovA.S. Sadykov Institute of Bioorganic Chemistry (UzAS), Tashkent, Uzbekistan.
Nodir Sh BerdievA.S. Sadykov Institute of Bioorganic Chemistry (UzAS), Tashkent, Uzbekistan.
Haji Akber AisaXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Ürümqi, China.
Jingshan ShenState Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Yechun XuState Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
H Eric XuState Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Xiangrui JiangState Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Leike ZhangWuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Natalia L VypovaA.S. Sadykov Institute of Bioorganic Chemistry (UzAS), Tashkent, Uzbekistan.
Dilshod Sh AllaberganovA.S. Sadykov Institute of Bioorganic Chemistry (UzAS), Tashkent, Uzbekistan.
Nigora A TagayalievaA.S. Sadykov Institute of Bioorganic Chemistry (UzAS), Tashkent, Uzbekistan.
Erkin I MusabaevScientific-Research Institute of Virology of the Ministry of the Health of Uzbekistan, Tashkent, Uzbekistan.
Gulnara A IbadovaCentre for the Development of Professional Qualification of Medical Workers, Tashkent, Uzbekistan.
Ilxom B RajabovCentre for the Development of Professional Qualification of Medical Workers, Tashkent, Uzbekistan.
Lyubov M LoktevaScientific-Research Institute of Virology of the Ministry of the Health of Uzbekistan, Tashkent, Uzbekistan.
Shanghai Institute of Materia Medica · CNChinese Academy of Sciences · CNMinistry of Health of the Republic of Uzbekistan · UZTashkent Pediatric Medical Institute · UZAcademy of Sciences Republic of Uzbekistan · UZXinjiang Technical Institute of Physics & Chemistry · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously, from the tannic sumac plant ( Clinical Trial Registration: ClinicalTrials.gov, ID NCT05862883.

Indexed as

3CLproclinical trialCOVID-19RdRpRhus coriariaRutanSARS-CoV-2

Identifiers

PMID38093975
PMCPMC10716264
OpenAlexW4389150858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.