Evidence map›Paper›PMID 38093856›Full record

ArticleData in brief2024

Data from a national survey of United States primary care physicians on genetic risk scores for common disease prevention.

Charles A Brunette, Elizabeth J Harris, Ashley A Antwi, Amy A Lemke, Benjamin J Kerman, Jason L Vassy

Abstract read
In one paragraph

Article in Data in brief, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charles A BrunetteVeterans Affairs Boston Healthcare System, Boston, MA, USA.
Elizabeth J HarrisVeterans Affairs Boston Healthcare System, Boston, MA, USA.
Ashley A AntwiVeterans Affairs Boston Healthcare System, Boston, MA, USA.
Amy A LemkeNorton Children's Research Institute, University of Louisville School of Medicine, Louisville, KY, USA.
Benjamin J KermanDepartment of Medicine, Harvard Medical School, Boston, MA, USA.
Jason L VassyVeterans Affairs Boston Healthcare System, Boston, MA, USA.

Funding

Pragmatic randomized trial of polygenic risk scoring for common diseases in primary careR35HG010706 · NHGRI · HARVARD MEDICAL SCHOOL · PI VASSY, JASON L · 2019 to 2024
$2.6M
NHGRI NIH HHS R35 HG010706
6 · The paper itself

Abstract

Genetic risk scores (GRS) are an emerging and rapidly evolving genomic medicine innovation that may contribute to more precise risk stratification for disease prevention. Inclusion of GRS in routine medical care is imminent, and understanding how physicians perceive and intend to utilize GRS in practice is an important first step in facilitating uptake. This dataset was derived from an electronic survey and comprises one of the first, largest, and broadest samples of United States primary care physician perceptions on the clinical decision-making, benefits, barriers, and utility of GRS to date. The dataset is nearly complete (<1% missing data) and contains responses from 369 PCPs spanning 58 column variables. The public repository includes minimally filtered, de-identified data, all underlying survey versions and items, a data dictionary, and associated analytic files.

Indexed as

Cardiovascular diseaseDisease preventionHealth disparitiesPolygenic risk scoresProstate cancer

Identifiers

PMID38093856
PMCPMC10716767

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.