Evidence map›Paper›PMID 38093831›Full record

ArticleACS pharmacology & translational science2023

Screening of Pancreatic Ribonuclease A Inhibitors from an Autodisplayed Fv-Antibody Library.

Jeong Soo Sung, Jaeyong Jung, Hyemin Hwang, Ji-Hong Bong, Min-Jung Kang, Joachim Jose, Misu Lee, Jae-Chul Pyun

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS pharmacology & translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jeong Soo SungDepartment of Materials Science and Engineering, Yonsei University, 50 Yonsei-Ro, Seodaemun-Gu, Seoul 03722, Korea.
Jaeyong JungDepartment of Materials Science and Engineering, Yonsei University, 50 Yonsei-Ro, Seodaemun-Gu, Seoul 03722, Korea.
Hyemin HwangDivision of Life Sciences, College of Life Science and Bioengineering, Incheon National University, Incheon 22012, Korea.
Ji-Hong BongDepartment of Materials Science and Engineering, Yonsei University, 50 Yonsei-Ro, Seodaemun-Gu, Seoul 03722, Korea.
Min-Jung KangKorea Institute of Science and Technology (KIST), Seoul 02792, Korea.
Joachim JoseInstitute of Pharmaceutical and Medical Chemistry, Westfälischen Wilhelms-Universität Münster, Münster 48149, Germany.ORCID https://orcid.org/0000-0002-0666-2676
Misu LeeDivision of Life Sciences, College of Life Science and Bioengineering, Incheon National University, Incheon 22012, Korea.
Jae-Chul PyunDepartment of Materials Science and Engineering, Yonsei University, 50 Yonsei-Ro, Seodaemun-Gu, Seoul 03722, Korea.ORCID https://orcid.org/0000-0001-9954-6860
Yonsei University · KRIncheon National University · KRKorea Institute of Science and Technology · KRUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ribonuclease A (RNase A) inhibitors were screened from an autodisplayed Fv-antibody library, which was prepared by randomizing amino acid sequences of the third complementary-determining region (CDR3) within the heavy chain variable region (V

Identifiers

PMID38093831
PMCPMC10714426
OpenAlexW4388859595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.