ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2023
From escalation to weaning strategies: how to integrate the ECMELLA concept.
Article in European heart journal supplements : journal of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Axial Flow Percutaneous Ventricular Assist Devices: Physiology, Procedural Considerations, and Clinical Applications-A State-of-the-Art Review.Structural heart : the journal of the Heart Team · 2026Review
- Transcatheter edge-to-edge mitral repair with a nitinol device in cardiogenic shock on micro-axial flow-pump support: a case report.European heart journal. Case reports · 2026Article
- Cost-effectiveness of combined veno-arterial extracorporeal membrane oxygenation and Impella support (ECPELLA) in infarct-related cardiogenic shock.European heart journal open · 2026Article
- Phase-Specific Hemodynamic Criteria and Outcomes in Patients With Cardiogenic Shock Receiving Percutaneous Ventricular Assist Devices.Journal of the American Heart Association · 2025Article
- Left atrial appendage cannulation for left ventricular unloading in a patient with ventricular thrombus on extracorporeal life support.Journal of cardiothoracic surgery · 2025Article
- Left ventricle unloading during veno-arterial extracorporeal membrane oxygenation: review with updated evidence.Acute and critical care · 2024Article
- Percutaneous Mechanical Circulatory Support in Acute Heart Failure Complicated with Cardiogenic Shock.Journal of clinical medicine · 2024Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The additional implantation of a micro-axial flow pump (mAFP) in patients receiving extracorporeal life support by a veno-arterial extracorporeal membrane oxygenation (V-A ECMO) for cardiogenic shock (CS) has gained interest in recent years. Thus far, retrospective propensity score-matched studies, case series, and meta-analyses have consistently shown an improved survival in patients treated with the so-called ECMELLA concept. The pathophysiological context is based on the modification of V-A ECMO-related side effects and the additive benefit of myocardial unloading. From this point of view, knowledge and detection of these pathophysiological mechanisms are of utmost importance to successfully manage mechanical circulatory support in CS. In this article, we describe best practices for the indication of the two devices as well as escalation and de-escalation approaches including implantation and explantation strategies that are key for success.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.