Evidence map›Paper›PMID 38093677›Full record

ArticleThe Journal of organic chemistry2024

Synthesis of Three-Dimensional Ring Fused Heterocycles by a Selective [4 + 2] Cycloaddition Between Bicyclic Thiazolo 2-Pyridones and Arynes.

Souvik Sarkar, Pardeep Singh, Simon Edin, Ola F Wendt, Fredrik Almqvist

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Souvik SarkarDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0003-1803-2708
Pardeep SinghDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.
Simon EdinCentre for Analysis and Synthesis, Lund University, SE-221 00 Lund, Sweden.
Ola F WendtCentre for Analysis and Synthesis, Lund University, SE-221 00 Lund, Sweden.ORCID 0000-0003-2267-5781
Fredrik AlmqvistDepartment of Chemistry, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0003-4646-0216

Funding

Rational design and synthesis of small molecule inhibitors targeting unique pathogenic mechanisms in Gram- and Gram+ bacteria important in UTIU19AI157797 · NIAID · WASHINGTON UNIVERSITY · PI ELLEBEDY, ALI HASSAN · 2021 to 2025
$11.4M
Chemical disarming of drug resistance in Mycobacterium tuberculosisR01AI134847 · NIAID · WASHINGTON UNIVERSITY · PI ALMQVIST, FREDRIK, STALLINGS, CHRISTINA LEIGH · 2018 to 2021
$2.7M
NIAID NIH HHS R01 AI134847NIAID NIH HHS U19 AI157797
6 · The paper itself

Abstract

A selective [4 + 2] cycloaddition reaction of thiazolo-2-pyridones with arynes has been demonstrated. The developed protocol allows rapid access to highly functionalized, structurally complex thiazolo-fused bridged isoquinolones in high yields, which are susceptible to further late-stage functionalization.

Identifiers

PMID38093677
PMCPMC10777404

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.