Evidence map›Paper›PMID 38093649›Full record

ArticleActa orthopaedica2023

Increased risk of aseptic loosening for posterior stabilized compared with posterior cruciate-retaining uncemented total knee replacements: a cohort study of 13,667 knees from the Dutch Arthroplasty Registry.

Raymond Puijk, Inger N Sierevelt, Bart G C W Pijls, Anneke Spekenbrink-Spooren, Peter A Nolte

Open access · goldAbstract read
In one paragraph

Article in Acta orthopaedica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
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  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Raymond PuijkDepartment of Orthopaedic Surgery, Spaarne Gasthuis, Hoofddorp. Rpuijk@spaarnegasthuis.nl.
Inger N SiereveltDepartment of Orthopaedic Surgery, Spaarne Gasthuis, Hoofddorp; Department of Orthopaedic Surgery, Xpert Clinics Orthopedic Amsterdam/Specialized Center of Orthopedic Research and Education, Amsterdam.
Bart G C W PijlsLandelijke Registratie Orthopedische Interventies (LROI; Dutch Arthroplasty Register), Bruistensingel 230, 5232 AD, 's Hertogenbosch; Department of Orthopaedics, Leiden University Medical Center (LUMC), Leiden.
Anneke Spekenbrink-SpoorenLandelijke Registratie Orthopedische Interventies (LROI; Dutch Arthroplasty Register), Bruistensingel 230, 5232 AD, 's Hertogenbosch.
Peter A NolteDepartment of Orthopaedic Surgery, Spaarne Gasthuis, Hoofddorp; Department of Oral Cell Biology, Academic Centre for Dentistry (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Spaarne Ziekenhuis · NLAcademic Center for Dentistry Amsterdam · NLLeiden University Medical Center · NLNetherlands Heart Registration · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeWhile registry studies have suggested a higher risk of revision for posterior-stabilized (PS) compared with posterior cruciate-retaining (CR) total knee replacements (TKR) using cement, it is unknown whether this is also the case for uncemented TKR. We aimed to compare the revision rates of PS and CR designs in patients receiving primary uncemented TKR. PATIENTS AND

methodsData from the Dutch arthroplasty register (LROI) was analyzed, comprising 12,226 uncemented primary CR TKRs and 750 uncemented PS TKRs registered between 2007 and 2022. Competing risk and multivariable Cox regression analyses were used to compare revision rates, risks of revision, and reasons for revision between groups. Sensitivity analyses were performed to analyze the risk, concerning the 5 most commonly used implants and performing hospitals for each group.

resultsUncemented PS TKRs had higher 10-year revision rates for any reason and aseptic loosening (6.5%, 95% confidence interval [CI] 4.6-9.2 and 3.9%, CI 2.6-6.7) compared with uncemented CR TKRs (4.2%, CI 3.8-4.7 and 1.4%, CI 1.2-1.7). PS TKRs were 1.4 and 2.5 times more likely to be revised for any reason and aseptic loosening, respectively. These results remained consistent after adjustment for age, sex, BMI, previous surgeries, bearing mobility, and surface modification, with sensitivity analyses.

conclusionWe found that uncemented PS implants have a higher rate of revision than uncemented CR implants, mainly due to a higher risk of aseptic loosening.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisCohort StudiesHumansProsthesis DesignProsthesis FailureRegistriesReoperation

Identifiers

PMID38093649
PMCPMC10719730
OpenAlexW4389741758

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.