Evidence map›Paper›PMID 38093648›Full record

ArticleHospital pediatrics2024

When to Transfer: Predictors of Pediatric High Flow Nasal Cannula Failure at a Community Hospital.

Kimiko S Dunbar, Sarah N Fox, Jacob F Thomas, Mark S Brittan, Gayle Soskolne, Jillian M Cotter

Open access · greenAbstract read
In one paragraph

Article in Hospital pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kimiko S DunbarSection of Pediatric Hospital Medicine, Children's Hospital Colorado, University of Colorado Denver, Aurora Colorado.
Sarah N FoxUniversity of Colorado School of Medicine, Aurora, Colorado.
Jacob F ThomasAdult and Child Consortium for Health Outcomes Research and Delivery Science.
Mark S BrittanSection of Pediatric Hospital Medicine, Children's Hospital Colorado, University of Colorado Denver, Aurora Colorado.
Gayle SoskolneSection of Pediatric Hospital Medicine, Children's Hospital Colorado, University of Colorado Denver, Aurora Colorado.
Jillian M CotterSection of Pediatric Hospital Medicine, Children's Hospital Colorado, University of Colorado Denver, Aurora Colorado.
University of Colorado Denver · USChildren's Hospital Colorado · US

Funding

Colorado Clinical and Translational Sciences Institute (CCTSI)UM1TR004399 · NCATS · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS, RONALD J. SOKOL · 2023 to 2026
$30.7M
CTSA K12 Program at University of Colorado DenverK12TR004412 · NCATS · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM · 2024 to 2026
$3.2M
NCATS NIH HHS K12 TR004412NCATS NIH HHS UM1 TR004399
6 · The paper itself

Abstract

objectivesTo identify risk factors of high flow nasal cannula (HFNC) failure at a US pediatric hospital without a co-located ICU.

methodsRetrospective cohort study of patients aged 0 to 18 years who were started on HFNC in the emergency department or inpatient unit at a community hospital over a 16-month period. Children with chronic medical conditions were excluded. Outcome was HFNC failure, defined as HFNC need greater than floor limit, noninvasive positive pressure, or mechanical ventilation. In bivariate analysis, we compared demographic and clinical factors between those with and without failure. We included variables in a multivariable model on the basis of statistical significance. We used Poisson regression with robust error variance to calculate the adjusted relative risk (aRR) of failure for each variable.

resultsOf 195 children, 51% had HFNC failure. In adjusted analysis, failure was higher in all age groups <12 months as compared with older children. For example, children aged 3 to 5 months had a higher risk of failure compared with patients 12 months or older (aRR 1.85, confidence interval [CI] 1.34-2.54). Patients with an asthma exacerbation had a higher risk of failure (aRR 1.39, CI 1.03-1.88). Patients whose respiratory rate or heart rate did not improve also had a higher risk of failure (aRR 1.73, CI 1.24-2.41; aRR 1.47, CI 1.14-1.90).

conclusionsPatients who were younger, had asthma, and did not have improved respiratory rate or heart rate after HFNC were more likely to experience HFNC failure.

Indexed as

AsthmaRespiratory InsufficiencyAdolescentCannulaChildHospitals, CommunityHumansOxygen Inhalation TherapyRespiration, ArtificialRetrospective Studies

Identifiers

PMID38093648
PMCPMC11321470
OpenAlexW4389739038

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.