ArticleThe American journal of psychiatry2024
Predicting Acute Changes in Suicidal Ideation and Planning: A Longitudinal Study of Symptom Mediators and the Role of the Menstrual Cycle in Female Psychiatric Outpatients With Suicidality.
Article in The American journal of psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Prevalence, Risk Factors, and Treatments for Suicidality in People Living with Premenstrual Dysphoric Disorder (PMDD): A Systematic Review.Administration and policy in mental health · 2026Pooled it
- Thymus Involution across the Human Menstrual Cycle.bioRxiv : the preprint server for biology · 2026Article
- Molecular Mechanisms of Menstrual Cycle-Related Suicide Risk: A Selective Review of Promising Candidate Systems.Biological psychiatry · 2026Review
- Affective Sensitivity to Ovarian Steroid Hormone Flux Across the Menstrual Cycle: Manifestations and Biopsychosocial Risk Factors.Annual review of clinical psychology · 2026Review
- Gendering the Menstrual Cycle in Behavioral Neuroendocrinology.American journal of human biology : the official journal of the Human Biology Council · 2026Review
- Sex difference in parental risk of suicide attempt during and after pregnancy in Sweden.Nature human behaviour · 2026Article
- Understanding the emergence of suicidal thoughts and behaviors in adolescence from a brain and behavioral developmental perspective.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Peripheral cyclical expression of GABA-A receptor subunit genes and menstrual cycle affective change: a dimensional, transdiagnostic study.Translational psychiatry · 2025Article
- Within-Person Changes in Daily Ovarian Hormone Levels Influence Genetic Effects on Emotional Eating in Women.The International journal of eating disorders · 2025Article
- Toward Precision Reproductive Psychiatry: A Call for Targeted, Transdiagnostic Approaches to Premenstrual Disorders.The American journal of psychiatry · 2025Article
- Unmasking the cycle: Premenstrual and menstrual exacerbation of psychiatric disorders and impact on female mental health.World journal of psychiatry · 2025Review
- Women's reproductive mental health: currently available evidence and future directions for research, clinical practice and health policy.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Targeted Research and Treatment Implications in Women With Depression.Focus (American Psychiatric Publishing) · 2025Review
- Suicidality should be considered for inclusion in the diagnostic criteria for PMDD.The lancet. Psychiatry · 2025Article
- The relationship between college students' Suicidal ideation and rejection sensitivity: a network analysis.BMC public health · 2025Article
- Dimensional Affective Sensitivity to Hormones across the Menstrual Cycle (DASH-MC): A transdiagnostic framework for ovarian steroid influences on psychopathology.Molecular psychiatry · 2025Review
- Breaking the cycle: Memorable messages of "grin n' bear it" and silence in menarche narrative recall.Qualitative research in medicine & healthcare · 2024Article
- A call to integrate menstrual cycle influences into just-in-time adaptive interventions for suicide prevention.Frontiers in psychiatry · 2024Article
- Menstrual Cycle Dynamics and Their Impact on Psychotherapy: Insights From a Mixed-Methods Study.Clinical psychology & psychotherapyArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveCross-sectional and preliminary longitudinal findings suggest that cyclical ovarian hormone fluctuations influence acute suicide risk. The authors provide the first analyses in females with suicidality to investigate which daily symptoms covary with suicidal ideation and planning thoughts, the role of the menstrual cycle in daily symptom variation, how daily fluctuations in symptoms mediate the menstrual cycle-suicidality relationship, and how these associations vary across individuals.
methodsNaturally cycling psychiatric outpatients (N=119) with past-month suicidal ideation provided daily ratings of psychiatric symptoms (depression, hopelessness, anxiety, feeling overwhelmed, agitation, anhedonia, worthlessness, rejection sensitivity, anger, perceived burdensomeness, and interpersonal conflict), suicidal ideation, and suicidal planning across at least one menstrual cycle. Symptom ratings were decomposed into trait (person-centered mean) and state (daily person-centered mean deviation) components. Five cycle phases were identified in relation to menses onset and ovulation (surge in urine luteinizing hormone level). Hypotheses were tested in multilevel structural equation models.
resultsNearly all psychiatric symptoms covaried with fluctuations in daily suicidal ideation, and a limited set of symptoms (depression, hopelessness, rejection sensitivity, and perceived burdensomeness) predicted within-person increases in suicidal planning. Many patients demonstrated perimenstrual worsening of psychiatric symptoms, suicidal ideation, and suicidal planning. Depressive symptoms (depression, hopelessness, perceived burdensomeness, and anhedonia) were the most robust statistical mediators predicting perimenstrual exacerbation of suicidality.
conclusionsResearch on the menstrual cycle and suicide has been limited historically by small, cross-sectional samples. This study provides the first evidence that measuring day-to-day correlates of suicidality in a large transdiagnostic sample of females with suicidal ideation can contribute to understanding the pathways by which the menstrual cycle influences acute suicide risk.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.