Evidence map›Paper›PMID 38093534›Full record

ArticleSe pu = Chinese journal of chromatography2023

[Preparation of a block copolymer-based temperature-responsive affinity chromatography stationary phase for antibody separation and purification].

Dongmei Guo, Yiran Xia, Ur Rahman Mujeeb, Jianzhong Wang, Jiawei Liu, Quan Bai

Open access · bronzeAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Se pu = Chinese journal of chromatography, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dongmei GuoKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Institute of Modern Separation Science, Key Laboratory of Modern Separation Science in Shaanxi Province, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China.
Yiran XiaKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Institute of Modern Separation Science, Key Laboratory of Modern Separation Science in Shaanxi Province, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China.
Ur Rahman MujeebKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Institute of Modern Separation Science, Key Laboratory of Modern Separation Science in Shaanxi Province, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China.
Jianzhong WangKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Institute of Modern Separation Science, Key Laboratory of Modern Separation Science in Shaanxi Province, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China.
Jiawei LiuKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Institute of Modern Separation Science, Key Laboratory of Modern Separation Science in Shaanxi Province, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China.
Quan BaiKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Institute of Modern Separation Science, Key Laboratory of Modern Separation Science in Shaanxi Province, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China.
Ministry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibodies play an essential role in cancer diagnosis and treatment because of the specificity for target biomolecules and reduction of side effects. However, antibodies separation and purification still face some challenges. Antibody elution from columns using a low-pH aqueous solution leads to aggregation or loss of activity of the antibody drugs. In this paper, a block copolymer-based temperature-responsive affinity chromatography (TRAC) stationary phase, SiO

Indexed as

AntibodiesSilicon DioxideChromatography, Affinitygamma-GlobulinsHumansLigandsPolymersSerum Albumin, BovineTemperatureAntibodiesgamma-GlobulinsLigandsPolymersSerum Albumin, BovineSilicon Dioxide4-vinylpyridineaffinity chromatographyantibody separationpoly(N-isopropylacrylamide)temperature-responsive chromatography

Identifiers

PMID38093534
PMCPMC10719812
OpenAlexW4389799533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.