Evidence map›Paper›PMID 38093385›Full record

ArticleAntimicrobial resistance and infection control2023

Antimicrobial use of patients with sexually transmitted infection symptoms prior to presentation at five health facilities in Southern Ghana.

Naiki Attram, Helena Dela, Eric Behene, Nicholas N A Kyei, Karen Ocansey, Jennifer N Yanney, Edward O Nyarko, Kennedy K Addo, Kwadwo A Koram, Anne Fox and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Naiki AttramNaval Medical Research Unit-EURAFCENT, Accra, Ghana. npuplampu@noguchi.ug.edu.gh.
Helena DelaNaval Medical Research Unit-EURAFCENT, Accra, Ghana.
Eric BeheneNaval Medical Research Unit-EURAFCENT, Accra, Ghana.
Nicholas N A KyeiGhana Armed Forces Health Directorate, 37 Military Hospital, Accra, Ghana.
Karen OcanseyNaval Medical Research Unit-EURAFCENT, Accra, Ghana.
Jennifer N YanneyNaval Medical Research Unit-EURAFCENT, Accra, Ghana.
Edward O NyarkoGhana Armed Forces Health Directorate, 37 Military Hospital, Accra, Ghana.
Kennedy K AddoNoguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana.
Kwadwo A KoramNoguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana.
Anne FoxNaval Medical Research Unit-EURAFCENT, Accra, Ghana.
Andrew LetiziaNaval Medical Research Unit-EURAFCENT, Accra, Ghana.
Terrel SandersNaval Medical Research Unit-EURAFCENT, Accra, Ghana.
Noguchi Memorial Institute for Medical Research · GHUniversity of Ghana · GH37 Military Hospital · GHUniversity Hospital Heidelberg · DE

Funding

Global Emerging Infections Surveillance (GEIS) Branch, US ProMIS ID P0028_18_N3_2.1
6 · The paper itself

Abstract

backgroundUnregulated and inappropriate antimicrobial use are major contributors to the evolution of antimicrobial resistance worldwide. It is important to monitor and collect data on the use of antibiotics at health facilities and in the general population in order to support antimicrobial stewardship programs.

methodsAs part of a gonorrhea surveillance study that was conducted from June 2012 to Jan 2018, we administered a questionnaire to elicit information on the types of antimicrobials used by individuals to treat symptoms of a gonorrhea infection prior to presenting at five health facilities in Southern Ghana.

resultsAlmost one-third (383/1,349; 28%) of study participants admitted taking one or more antimicrobial types before hospital presentation, while 138/383 (36%) of those who took antimicrobials could not remember what they ingested. A greater percentage of individuals who reported prior antimicrobial use before presentation at a health facility tested positive for gonorrhea by NAAT (30%), in contrast to 24% for those without prior treatment (p = 0.004). Penicillin and its derivatives, as well as ciprofloxacin and doxycycline, were the most used, while a few individuals reported taking drugs such as kanamycin and rifampin. Males were more likely than females to take an antimicrobial prior to attending a health center.

conclusionIn order to curb excessive and inappropriate antimicrobial use, antibiotics used by patients before presenting at hospitals ought to be investigated by healthcare providers. It is recommended that health professionals receive continuing education on the consequences of unregulated antimicrobial use.

Indexed as

Anti-Infective AgentsGonorrheaSexually Transmitted DiseasesAnti-Bacterial AgentsFemaleGhanaHealth FacilitiesHumansMaleMicrobial Sensitivity TestsNeisseria gonorrhoeaeAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial resistanceAntimicrobial stewardshipAntimicrobial useGonorrhea treatment

Identifiers

PMID38093385
PMCPMC10720218
OpenAlexW4389670800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.