ArticleScandinavian journal of trauma, resuscitation and emergency medicine2023
Pre-hospital ECPR in an Australian metropolitan setting: a single-arm feasibility assessment-The CPR, pre-hospital ECPR and early reperfusion (CHEER3) study.
Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Application of Machine Learning for Patients With Cardiac Arrest: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Modelling eCPR eligibility after out-of-hospital cardiac arrest: a 10-year retrospective temporospatial analysis from a mixed urban-rural region in Germany.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Article
- Ethics in prehospital extracorporeal cardiopulmonary resuscitation.Resuscitation plus · 2026Article
- The impact of interdisciplinary cardiac arrest teams on paramedic practise: an interpretive qualitative study using reflexive thematic analysis.Resuscitation plus · 2026Article
- Prehospital initiation of extracorporeal life support for refractory out-of-hospital cardiac arrest-results of a prospective observational study.Critical care (London, England) · 2026Observational
- Cost effectiveness of pre-hospital extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest - An analysis of the PRECARE study.Resuscitation plus · 2026Article
- Implementation of emergency extracorporeal membrane oxygenation in a hospital without on-site cardiothoracic surgery support.Resuscitation plus · 2026Article
- Impact of prehospital extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest on survival with good neurological function: a systematic review and meta-analysis.Resuscitation plus · 2025Review
- Extracorporeal membrane oxygenation (ECMO) rescue for unanticipated failed airway management - Fact or Fiction?Indian journal of anaesthesia · 2025Article
- Contemporary Practices in Refractory Out-of-Hospital Cardiac Arrest: A Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Estimated caseload for a rotary wing prehospital extra-corporeal cardio-pulmonary resuscitation service in North West England: A retrospective eligibility study.Resuscitation plus · 2025Article
- Early fluid balance and mortality following extracorporeal cardiopulmonary resuscitation: a high volume, single center study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Observational
- Assess, improve, detect, guide: a narrative review and proposal for a standardized protocol for prehospital transesophageal echocardiography during out-of-hospital cardiac arrest.The ultrasound journal · 2025Review
- A training programme for novice extracorporeal resuscitation providers.Resuscitation plus · 2024Article
- ECPR-the evolving role in cardiac arrest.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024Review
- Machine learning prediction of refractory ventricular fibrillation in out-of-hospital cardiac arrest using features available to EMS.Resuscitation plus · 2024Article
- Temporal trends in the incidence and outcomes of shock-refractory ventricular fibrillation out-of-hospital cardiac arrest.Resuscitation plus · 2024Article
Corrections and comments
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Authors and funding
26 authors at 2 institutions in 1 country.
Funding
Abstract
introductionSurvival from refractory out of hospital cardiac arrest (OHCA) without timely return of spontaneous circulation (ROSC) utilising conventional advanced cardiac life support (ACLS) therapies is dismal. CHEER3 was a safety and feasibility study of pre-hospital deployed extracorporeal membrane oxygenation (ECMO) during cardiopulmonary resuscitation (ECPR) for refractory OHCA in metropolitan Australia.
methodsThis was a single jurisdiction, single-arm feasibility study. Physicians, with pre-existing ECMO expertise, responded to witnessed OHCA, age < 65 yrs, within 30 min driving-time, using an ECMO equipped rapid response vehicle. If pre-hospital ECPR was undertaken, patients were transported to hospital for investigations and therapies including emergent coronary catheterisation, and standard intensive care (ICU) therapy until either cardiac and neurological recovery or palliation occurred. Analyses were descriptive.
resultsFrom February 2020 to May 2023, over 117 days, the team responded to 709 "potential cardiac arrest" emergency calls. 358 were confirmed OHCA. Time from emergency call to scene arrival was 27 min (15-37 min). 10 patients fulfilled the pre-defined inclusion criteria and all were successfully cannulated on scene. Time from emergency call to ECMO initiation was 50 min (35-62 min). Time from decision to ECMO support was 16 min (11-26 min). CPR duration was 46 min (32-62 min). All 10 patients were transferred to hospital for investigations and therapy. 4 patients (40%) survived to hospital discharge neurologically intact (CPC 1/2).
conclusionPre-hospital ECPR was feasible, using an experienced ECMO team from a single-centre. Overall survival was promising in this highly selected group. Further prospective studies are now warranted.
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Registered trials
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