ArticleBMC cardiovascular disorders2023
Serum magnesium level and cardiac valve calcification in hemodialysis patients.
Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Prevalence and factors associated with pulmonary hypertension in patients undergoing maintenance hemodialysis: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Serum Visfatin Level and Cardiac Valve Calcifcation in Hemodialysis Patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Article
- Clinical Characteristics and Risk Factors for Major Adverse Cardiovascular Events in Patients on Maintenance Hemodialysis: A Retrospective Study.International journal of general medicine · 2026Article
- Valvular calcification in chronic kidney disease: new insights from recent clinical and preclinical studies.Clinical kidney journal · 2025Article
- Study of plasma essential element concentrations to explore markers of acute myocardial infarction.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Correlation between visceral fat area and cardiac valve calcification in hemodialysis patients.Frontiers in cardiovascular medicine · 2025Article
- Analysis of risk factors and application of risk management strategies in hemodialysis patients complicated with heart failure.Frontiers in cardiovascular medicine · 2025Article
- Nitrogen-containing bisphosphonate induces enhancement of OPG expression and inhibition of RANKL expression via inhibition of farnesyl pyrophosphate synthase to inhibit the osteogenic differentiation and calcification in vascular smooth muscle cells.BMC cardiovascular disorders · 2024Article
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Authors and funding
3 authors at 2 institutions in 1 country.
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Abstract
introductionCardiac valve calcification is closely related to cardiovascular disease. The aim of this study was to investigate the magnesium level and cardiac valve calcification in hemodialysis patients.
methodsA cross-sectional study was conducted in 105 maintenance hemodialysis patients with complete follow-up data from June 2020 to May 2021 in Beijing Tsinghua Changgung Hospital, Tsinghua University. Baseline data, including sex, age, primary disease, liver and kidney function, electrolytes and parathyroid hormone, were recorded. According to their echocardiograms, patients were divided into a cardiac valve calcification group and a noncardiac valve calcification group, and the correlations between valve calcification and clinical data were analyzed.
resultsOf 105 patients under hemodialysis, 60 (56.6%) were male, with an average age of 62.1 ± 13.5 years and a mean dialysis duration of 58.8 ± 45.4 months. The majority of primary renal diseases were diabetic nephropathy (55, 51.9%). Approximately 64.8% of the 105 maintenance hemodialysis patients had cardiac valve calcification, and 35.2% were in the noncardiac valve calcification group. The independent t test and the chi-square test analysis showed that the cardiac valve calcification group had older age, higher smoking rate, diabetes mellitus, lower extremity arterial occlusion, coronary heart disease, and coronary artery calcification ratio but lower parathyroid hormone, serum calcium, serum magnesium, albumin, prealbumin, and high-density lipoprotein cholesterol levels (P < 0.05). Logistic regression analysis showed that age, diabetes mellitus, coronary artery calcification, lower serum magnesium, lower serum calcium, and lower parathyroid hormone levels were associated with valve calcification.
conclusionThe presence of cardiac valve calcification was associated with age, calcium, phosphorus and lower magnesium level. These factors we should pay more attention in clinical practice.
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