ArticleBMC geriatrics2023
Predictors for quality of life in older adults: network analysis on cognitive and neuropsychiatric symptoms.
Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- How health literacy and eHealth literacy influence quality of life in older adults with chronic diseases: a network and path analysis.Health and quality of life outcomes · 2026Article
- Social health indicators promoting quality of life for the older people in the Kingdom of Saudi Arabia.Frontiers in public health · 2026Article
- Relationship between depression, neuropsychiatric symptoms and cognitive profiles of the elderly in India: An assessment using the ICMR-MUDRA toolbox.Global mental health (Cambridge, England) · 2026Article
- Association of quality of life in older patients with breast cancer: a cross-sectional study from China.BMJ open · 2025Observational
- Insights into anesthesia administration for elderly individuals undergoing painless gastroenteroscopy: A bibliometric study.World journal of gastrointestinal endoscopy · 2025Article
- Network analysis of depressive symptoms, cognitive functioning, and life satisfaction among healthcare workers.Frontiers in psychiatry · 2025Article
- Effect of a short-term water-based exercise program on cognitive skills in a Mexican older adult population.Frontiers in human neuroscience · 2025Article
- Subjective Cognitive Impairment and Physical Activity: Investigating Risk Factors and Correlations among Older Adults in Spain.Journal of functional morphology and kinesiology · 2024Article
- Assessing the Impact of Multidisciplinary Collaboration on Quality of Life in Older Patients Receiving Primary Care: Cross Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundQuality of life (QoL) of older adults has become a pivotal concern of the public and health system. Previous studies found that both cognitive decline and neuropsychiatric symptoms (NPS) can affect QoL in older adults. However, it remains unclear how these symptoms are related to each other and impact on QoL. Our aim is to investigate the complex network relationship between cognitive and NPS symptoms in older adults, and to further explore their association with QoL.
methodsA cross-sectional study was conducted in a sample of 389 older individuals with complaints of memory decline. The instruments included the Neuropsychiatric Inventory, the Mini Mental State Examination, and the 36-item Short Form Health Survey. Data was analyzed using network analysis and mediation analysis.
resultsWe found that attention and agitation were the variables with the highest centrality in cognitive and NPS symptoms, respectively. In an exploratory mediation analysis, agitation was significantly associated with poor attention (β = -0.214, P < 0.001) and reduced QoL (β = -0.137, P = 0.005). The indirect effect of agitation on the QoL through attention was significant (95% confidence interval (CI) [-0.119, -0.035]). Furthermore, attention served as a mediator between agitation and QoL, accounting for 35.09% of the total effect.
conclusionsBy elucidating the NPS-cognition-QoL relationship, the current study provides insights for developing rehabilitation programs among older adults to ensure their QoL.
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