Evidence map›Paper›PMID 38093036›Full record

ArticleInternational journal of colorectal disease2023

Fistula development after anal abscess drainage-a multicentre retrospective cohort study.

Daniel Mark Skovgaards, Helene Perregaard, Christian Bakholdt Dibbern, Andreas Nordholm-Carstensen

Registry-linked trialOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in International journal of colorectal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07704359 (Randomized Antibiotics for Prevention of Fistula After Incision and Drainage of First-Episode Perianal Abscess), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07704359 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Randomized Antibiotics for Prevention of Fistula After Incision and Drainage of First-Episode Perianal Abscess (RAPID): A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2026 to 2029Enrolled236ConditionsPerianal Abscess, Anal FistulaArmsAmoxicillin + Clavulanate, Ciprofloxacin + Metronidazole
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Treatment method selection for perianal abscesses: bedside or operating room? a single center, retrospective study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Daniel Mark SkovgaardsDigestive Disease Center, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. danielskovgaards@gmail.com.ORCID http://orcid.org/0000-0003-3270-5956
Helene PerregaardSurgical Department, Nordsjællands Hospital, University of Copenhagen, Hillerød, Denmark.
Christian Bakholdt DibbernThe Gastrointestinal Unit, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark.
Andreas Nordholm-CarstensenDigestive Disease Center, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKNordsjællands Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAnal abscesses are common and, despite correct treatment with surgical drainage, carry the risk of developing fistulas. Studies identifying risk factors for the development of anal fistulas are sparse. This study aimed to identify the risk factors for anal fistulas after anal abscess surgery.

methodsThis was a multicentre, retrospective cohort study of patients undergoing acute surgery for anal abscesses in the Capital Region of Denmark between 2018 and 2019. The patients were identified using ICD-10 codes for anal abscesses. Predefined clinicopathological factors and postoperative courses were extracted from patient records.

resultsA total of 475 patients were included. At a median follow-up time of 1108 days (IQR 946-1320 days) following surgery, 164 (33.7%) patients were diagnosed with an anal fistula. Risk factors for developing fistulas were low intersphincteric (OR 2.77, 95CI 1.50-5.06) and ischioanal (OR 2.48, 95CI 1.36-4.47) abscesses, Crohn's disease (OR 5.96, 95CI 2.33-17.2), a history of recurrent anal abscesses (OR 4.14, 95CI 2.47-7.01) or repeat surgery (OR 5.96, 95CI 2.33-17.2), E. coli-positive pus cultures (OR 4.06, 1.56-11.4) or preoperative C-reactive protein (CRP) of more than 100 mg/L (OR 3.21, 95CI 1.57-6.71).

conclusionSeveral significant clinical risk factors were associated with fistula development following anal abscess surgery. These findings are clinically relevant and could influence the selection of patients for specialised follow-up, facilitate expedited diagnosis, and potentially prevent unnecessarily long treatment courses.

Indexed as

Anus DiseasesRectal FistulaAbscessDrainageEscherichia coliHumansRetrospective StudiesTreatment OutcomeAnal abscessesCrohn’s diseaseFistula

Identifiers

PMID38093036
PMCPMC10719138
OpenAlexW4389670808

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.