Trial reportNature2024
Bioactive glycans in a microbiome-directed food for children with malnutrition.
Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph
Trial report in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 56 citations in OpenAlex.
- A microbiome-directed therapeutic food for children recovering from severe acute malnutrition.Science translational medicine · 2024Trial
- A microbiota-directed complementary food intervention in 12-18-month-old Bangladeshi children improves linear growth.EBioMedicine · 2024Trial
- Towards optimizing the host response to biotics: a report of an International Scientific Association for Probiotics and Prebiotics working group.Gut microbes · 2026Article
- Bridging the gap:Gut microbes · 2026Review
- Article
- Exploring the hypothetical role ofMicrobiology spectrum · 2026Article
- Reply to Wang et al.: Linking microbial metabolites and gut epithelial responses to microbiome-directed therapeutic foods.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Gut microbiome associations with acute malnutrition relapse in South Sudan.Microbiology spectrum · 2026Article
- Gut microbiome in preterm infants with different weight gain outcomes.Gut microbiology · 2026Article
- A single-strain dropout screen reveals mechanistic links between microbial ecology and metabolism.bioRxiv : the preprint server for biology · 2026Article
- Beyond malaria prevention: sulfadoxine-pyrimethamine treatment in pregnancy selectively remodels the maternal gut microbiome to increase gestational weight gain and improve birthweight.medRxiv : the preprint server for health sciences · 2026Article
- Enhancing inference of differential gene expression in metatranscriptomes from human microbial communities.Nature communications · 2026Article
- Gut microbial diversity impacts carbohydrate fermentation by children with severe acute malnutrition.iScience · 2026Article
- Exploring differences in the human gut microbiome between Han Chinese and non-Chinese populations.Genome biology · 2026Article
- A Hadza-enrichedGut microbes reports · 2026Article
- The Japanese gut microbiome: ecology, uniqueness, and impact on health and disease.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2026Review
- Glycoside hydrolase-mediated glucomannan catabolism inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Using gnotobiotic mice to decipher effects of gut microbiome repair in undernourished children on tuft and goblet cell function.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- New insights in amino sugar metabolism by the gut microbiome.Gut microbes · 2025Review
- Effects of intergenerational transmission of small intestinal bacteria cultured from stunted Bangladeshi children with enteropathy.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
- Update of
Authors and funding
29 authors at 7 institutions in 6 countries.
Matthew C Hibberd *Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0001-6520-677X
Daniel M Webber *Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0001-6109-8118
Dmitry A RodionovInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Suzanne HenrissatEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.
Robert Y ChenEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.
Cyrus ZhouEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0003-4335-6894
Hannah M LynnEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0002-6063-5820
Yi WangEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.
Hao-Wei ChangEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0002-1160-7452
Evan M LeeEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.
Janaki Lelwala-GurugeEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.
Marat D KazanovFaculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Aleksandr A ArzamasovInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID 0000-0002-4150-4817
Semen A LeynInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Vincent LombardArchitecture et Fonction des Macromolécules Biologiques, CNRS, Aix-Marseille University, Marseille, France.
Nicolas TerraponArchitecture et Fonction des Macromolécules Biologiques, CNRS, Aix-Marseille University, Marseille, France.ORCID 0000-0002-3693-6017
Bernard HenrissatDepartment of Biotechnology and Biomedicine (DTU Bioengineering), Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0002-3434-8588
Juan J CastilloDepartment of Chemistry, University of California, Davis, Davis, CA, USA.ORCID 0000-0001-9680-5273
Garret CoutureDepartment of Chemistry, University of California, Davis, Davis, CA, USA.
Nikita P BacalzoDepartment of Chemistry, University of California, Davis, Davis, CA, USA.ORCID 0000-0002-6253-6340
Ye ChenEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0002-6379-1968
Carlito B LebrillaDepartment of Chemistry, University of California, Davis, Davis, CA, USA.ORCID 0000-0001-7190-5323
Ishita MostafaInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Subhasish DasInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mustafa MahfuzInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Michael J BarrattEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.
Andrei L OstermanInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID 0000-0002-3810-9824
Tahmeed AhmedInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Jeffrey I GordonEdison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA. jgordon@wustl.edu.ORCID 0000-0001-8304-3548
Washington University in St. Louis · USInternational Centre for Diarrhoeal Disease Research · BDSanford Burnham Prebys Medical Discovery Institute · USUniversity of California, Davis · USCentre National de la Recherche Scientifique · FRKing Abdulaziz University · SASabancı Üniversitesi · TR
Funding
NATIONAL RESEARCH SERVICE AWARD-MEDICAL SCIENTISTT32GM007200 · NIGMS · WASHINGTON UNIVERSITY · PI YOKOYAMA, WAYNE M. · 1985 to 2024
$59.8MWashington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2MREGULATION OF GENE EXPRESSION - SMALL INTESTINER01DK030292 · NIDDK · WASHINGTON UNIVERSITY · PI JEFFREY I GORDON, ANDREI L OSTERMAN · 1986 to 2026
$6.5MREGULATION OF GENE EXPRESSION IN THE SMALL INTESTINER37DK030292 · NIDDK · WASHINGTON UNIVERSITY · PI GORDON, JEFFREY I · 1993 to 2015
$4.0MKey gut microbes shape intestinal epithelial lineage development, differentiation and metabolic functionK01DK134840 · NIDDK · WASHINGTON UNIVERSITY · PI Yi Wang · 2023 to 2026
$571kMechanism of action of a microbiota-directed complementary food that promotes ponderal growth in Bangladeshi children with moderate acute malnutritionF30DK131866 · NIDDK · WASHINGTON UNIVERSITY · PI ZHOU, CYRUS · 2022 to 2024
$138kNIDDK NIH HHS F30 DK131866NIDDK NIH HHS K01 DK134840NIDDK NIH HHS P30 DK056341NIDDK NIH HHS R01 DK030292NIDDK NIH HHS R37 DK030292NIGMS NIH HHS T32 GM007200
Abstract
Evidence is accumulating that perturbed postnatal development of the gut microbiome contributes to childhood malnutrition
Indexed as
FoodGastrointestinal MicrobiomeMalnutritionPolysaccharidesBacteriaBangladeshBody WeightFecesGenome, BacterialHumansInfantMetagenomeWeight GainPolysaccharides
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.