ArticleNature2023
Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes.
Open access · hybridAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
10.4field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Risk factors for pulmonary infection in patients with non-small cell lung cancer: a Meta-analysis.BMC pulmonary medicine · 2024Pooled it
- Effects of Baloxavir Marboxil Plus Neuraminidase Inhibitor vs Neuraminidase Inhibitor in High-risk Patients Hospitalized With Severe Influenza: A Post Hoc Analysis of the Flagstone Trial.Open forum infectious diseases · 2025Trial
- Blocking AGEs reduces airway epithelial viral susceptibility in diabetes-exacerbated COPD.EMBO molecular medicine · 2026Article
- Diabetes-associatedMicrobiology spectrum · 2026Observational
- Article
- Diabetes Mellitus with Influenza Virus and Subsequent Bacterial Infection: Triple Pathological Interactions and Challenges.International journal of molecular sciences · 2026Review
- The nicotinamide phosphoribosyltransferase inhibitor FK866 restricts influenza A virus replication by perturbing viral polymerase activity.Journal of virology · 2026Article
- Determinants of COVID-19 and Influenza Vaccination Among People with Diabetes Mellitus in Primary Health Care.Vaccines · 2026Article
- PRMT6 inhibition or deficiency attenuates diabetic neuropathic pain in male mice and is associated with reduced spinal neuroinflammation, microgliosis, and altered p53-p21 signaling.Journal of neuroinflammation · 2026Article
- Immune cell disorder in viral pneumonia.Journal of translational medicine · 2026Review
- TRIM5 integrates hypoglycemic stress and influenza infection.Nature communications · 2026Article
- Development and validation of an Occupational Hazards Index (OHI) and its association with hypertension-diabetes comorbidity in steel workers: a prospective cohort study.BMC public health · 2026Article
- Advanced Glycation End-Products Contribute to Delayed Diabetic Corneal Epithelial Wound Healing via the TLR4 Signaling.Investigative ophthalmology & visual science · 2026Article
- Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection.Nature communications · 2026Article
- Organ cross-talk: molecular mechanisms, biological functions, and therapeutic interventions for diseases.Signal transduction and targeted therapy · 2026Review
- Effects of metabolic syndrome on pulmonary infection in pediatric bronchial asthma: a narrative review.Frontiers in pediatrics · 2026Review
- Nonlinear association between stress hyperglycemia ratio and mortality in AHRF: validation through consensus clustering and supervised machine learning models.Frontiers in endocrinology · 2026Article
- Transcending risk factors: the implications of redefining diabetes as an immunometabolic disease for infectious disease studies.Frontiers in immunology · 2026Review
- Multi-omics reveals regulatory networks and critical early-warning factors for severe disease progression in diabetic patients infected with SARS-CoV-2.Frontiers in immunology · 2026Observational
- Review
Corrections and comments
- Commented on by
Authors and funding
30 authors at 7 institutions in 4 countries.
Samuel Philip Nobs *Systems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0003-0627-892X
Aleksandra A Kolodziejczyk *Systems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-2903-8884
Lital AdlerDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Nir HoreshSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-2459-8567
Christine BotscharnikowSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Ella HerzogSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Gayatree MohapatraSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Sophia HejndorfSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-2539-2413
Ryan-James HodgettsSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Igor SpivakSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Lena SchorrDivision of Microbiome & Cancer, DKFZ, Heidelberg, Germany.ORCID 0000-0002-3781-5663
Leviel FluhrSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Denise KviatcovskySystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-9697-0380
Anish ZachariaThe Institute for Drug Research, Hebrew University of Jerusalem, Jerusalem, Israel.
Suzanne NjukiThe Institute for Drug Research, Hebrew University of Jerusalem, Jerusalem, Israel.
Dinorah BaraschThe Institute for Drug Research, Hebrew University of Jerusalem, Jerusalem, Israel.
Noa StettnerDepartment of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
Mally Dori-BachashSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Alon HarmelinDepartment of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
Alexander BrandisDepartment of Biological Services, Weizmann Institute of Science, Rehovot, Israel.
Tevie MehlmanDepartment of Biological Services, Weizmann Institute of Science, Rehovot, Israel.
Ayelet ErezDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-9696-0393
Yiming HeSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Sara FerriniSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Jens PuschhofDivision of Microbiome & Cancer, DKFZ, Heidelberg, Germany.ORCID 0000-0001-9275-4034
Hagit ShapiroSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-0444-1781
Manfred KopfInstitute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland.
Arieh MoussaieffThe Institute for Drug Research, Hebrew University of Jerusalem, Jerusalem, Israel.
Suhaib K AbdeenSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel. suhib.abdin@weizmann.ac.il.ORCID 0009-0008-6787-1069
Eran ElinavSystems Immunology Department, Weizmann Institute of Science, Rehovot, Israel. eran.elinav@weizmann.ac.il.ORCID 0000-0002-5775-2110
Weizmann Institute of Science · ILHebrew University of Jerusalem · ILHeidelberg University · DEETH Zurich · CHGerman Cancer Research Center · DEInternational Institute of Molecular and Cell Biology · PLTel Aviv University · IL
Funding
Wellcome Trust
Abstract
People with diabetes feature a life-risking susceptibility to respiratory viral infection, including influenza and SARS-CoV-2 (ref.
Indexed as
Dendritic CellsDiabetes ComplicationsDiabetes MellitusDisease SusceptibilityHyperglycemiaLungVirus DiseasesAcetylationAcetyl Coenzyme AAnimalsChromatinDisease Models, AnimalGlucoseHistonesHumansMiceAcetyl Coenzyme AChromatinGlucoseHistones
Identifiers
What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.