Evidence map›Paper›PMID 38093010›Full record

ArticleNature2024

Slide-tags enables single-nucleus barcoding for multimodal spatial genomics.

Andrew J C Russell, Jackson A Weir, Naeem M Nadaf, Matthew Shabet, Vipin Kumar, Sandeep Kambhampati, Ruth Raichur, Giovanni J Marrero, Sophia Liu, Karol S Balderrama and 8 more

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 154 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
154citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

154 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Insights Into Spatial Transcriptomics: Exploring Recent Technical Developments and Their Diverse Applications.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  6. Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

94 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Andrew J C Russell *Broad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0001-5411-2807
Jackson A Weir *Broad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0001-8741-1344
Naeem M Nadaf *Broad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0002-7805-8523
Matthew ShabetBroad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0009-0000-7584-2841
Vipin KumarBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Sandeep KambhampatiBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Ruth RaichurBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Giovanni J MarreroBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Sophia LiuBroad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0003-3614-9731
Karol S BalderramaBroad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0001-8458-1364
Charles R VanderburgBroad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0001-8979-5054
Vignesh ShanmugamBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Luyi TianBroad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0003-3420-3685
J Bryan IorgulescuBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Charles H YoonDepartment of Surgical Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1231-3840
Catherine J WuBroad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0002-3348-5054
Evan Z MacoskoBroad Institute of Harvard and MIT, Cambridge, MA, USA. emacosko@broadinstitute.org.ORCID 0000-0002-2794-5165
Fei ChenBroad Institute of Harvard and MIT, Cambridge, MA, USA. chenf@broadinstitute.org.ORCID 0000-0003-2308-3649

Funding

An Atlas of Human Brain Cell VariationUM1MH130966 · NIMH · BROAD INSTITUTE, INC. · PI Evan Z Macosko, Steven Andrew McCarroll · 2022 to 2026
$67.5M
MOLECULAR BIOPHYSICS TRAINING GRANTT32GM008313 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MURTHY, VENKATESH N · 1989 to 2023
$14.6M
COVID19 Slide-seqR01HG010647 · NHGRI · BROAD INSTITUTE, INC. · PI Fei Chen, Evan Z Macosko · 2019 to 2026
$6.0M
Spatial genomic tools to interrogate T cell clonotypes, tumor clones and the microenvironmentR01CA276865 · NCI · BROAD INSTITUTE, INC. · PI Fei Chen, Catherine Ju-Ying Wu · 2023 to 2026
$2.8M
Implementation of Slide-seq for high-resolution, whole-transcriptome human tissue maps.UH3CA246632 · NCI · BROAD INSTITUTE, INC. · PI MACOSKO, EVAN Z · 2019 to 2021
$1.9M
A Platform for Scalable Spatial Somatic Variant ProfilingUG3NS132135 · NINDS · BROAD INSTITUTE, INC. · PI BUENROSTRO, JASON DANIEL, CHEN, FEI · 2023 to 2024
$751k
NCI NIH HHS UH3 CA246632NHGRI NIH HHS R01 HG010647NINDS NIH HHS UG3 NS132135
6 · The paper itself

Abstract

Recent technological innovations have enabled the high-throughput quantification of gene expression and epigenetic regulation within individual cells, transforming our understanding of how complex tissues are constructed

Indexed as

DNA Barcoding, TaxonomicGenomicsAnimalsBrainChromatinEpigenesis, GeneticGene Expression ProfilingHippocampusHumansLigandsMelanomaMiceOrgan SpecificityPalatine TonsilReceptors, Antigen, T-CellResponse ElementsChromatinLigandsReceptors, Antigen, T-CellRNATranscription Factors

Identifiers

PMID38093010
PMCPMC10764288

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.