ArticleNature2023
Indigenous Australian genomes show deep structure and rich novel variation.
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Large estimated size of the Australian Indigenous population before its extensive decline following colonial invasion.Nature human behaviour · 2026Article
- Newborn Screening: Equity for Aboriginal and Torres Strait Islander Families in the Context of Emerging Genomics.The Medical journal of Australia · 2026Article
- Rare disease genomics in an era of human pangenomics and telomere-to-telomere genome references.European journal of human genetics : EJHG · 2026Review
- Article
- Translating multi-omics into healthcare: requisites for scalable and equitable implementation.Human genomics · 2026Review
- Article
- Regional autozygosity association with albumin-to-creatinine ratio reveals a novel FTO region in an Indigenous Australian population.European journal of human genetics : EJHG · 2025Article
- The Expression of SIRT3 in Endometrial Carcinoma and Its Effect on Promoting Apoptosis of Ishikawa Cells.Biochemical genetics · 2025Article
- Recent Statistical Innovations in Human Genetics.Annals of human genetics · 2025Review
- Patterns of genetic admixture reveal similar rates of borrowing across diverse scenarios of language contact.Science advances · 2025Article
- Indel calling from ONT sequencing data of family trios via sparse attention and 3D convolution.Briefings in bioinformatics · 2025Article
- Disease progression & treatment need in sub-genotype C4 hepatitis B infection: a retrospective cohort study in the Northern Territory, Australia.BMC infectious diseases · 2025Article
- Isolated clubfoot in the Northern Territory of Australia: birth prevalence and population description.International journal of epidemiology · 2025Article
- A High-Resolution Genomic Study of the Pama-Nyungan Speaking Yolngu People of Northeast Arnhem Land, Australia.American journal of biological anthropology · 2025Article
- Article
- A call to action to scale up research and clinical genomic data sharing.Nature reviews. Genetics · 2025Review
- Type-2 diabetes epigenetic biomarkers: present status and future directions for global and Indigenous health.Frontiers in molecular biosciences · 2025Review
- Estimating evolutionary and demographic parameters via ARG-derived IBD.PLoS genetics · 2025Article
- A bioinformatic analysis of gene editing off-target loci altered by common polymorphisms, using 'PopOff'.Journal of the Royal Society of New Zealand · 2025Article
- Implementing genomic medicine in New Zealand.Journal of the Royal Society of New Zealand · 2025Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Indigenous peoples of Australia have a rich linguistic and cultural history. How this relates to genetic diversity remains largely unknown because of their limited engagement with genomic studies. Here we analyse the genomes of 159 individuals from four remote Indigenous communities, including people who speak a language (Tiwi) not from the most widespread family (Pama-Nyungan). This large collection of Indigenous Australian genomes was made possible by careful community engagement and consultation. We observe exceptionally strong population structure across Australia, driven by divergence times between communities of 26,000-35,000 years ago and long-term low but stable effective population sizes. This demographic history, including early divergence from Papua New Guinean (47,000 years ago) and Eurasian groups
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.