Evidence map›Paper›PMID 38092887›Full record

ArticleScientific reports2023

Epidemiological and clinical features of SARS-CoV-2 Omicron variant infection in Quanzhou, Fujian province: a retrospective study.

Huatang Zhang, Zhangyan Weng, Yijuan Zheng, Minghui Zheng, Wenhuang Chen, Haoyi He, Xiaoyi Ye, Youxian Zheng, Jianfeng Xie, Kuicheng Zheng and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Huatang Zhang *Department of Infection Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Zhangyan Weng *Department of Infection Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Yijuan Zheng *Department of Infection Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Minghui Zheng *Department of Infection Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Wenhuang ChenDepartment of Infection Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Haoyi HeDepartment of Infection Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Xiaoyi YeDepartment of Respiratory Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Youxian ZhengDepartment of Clinical Laboratory, Quanzhou Center for Disease Control and Prevention, No. 21 Jinhuai Street, Fengze District, Quanzhou, 362000, Fujian, China.
Jianfeng XieFujian Provincial Key Laboratory of Zoonosis Research, Fujian Center for Disease Control and Prevention, No. 76 Jintai Road, Gulou District, Fuzhou, 350001, Fujian, China.
Kuicheng ZhengFujian Provincial Key Laboratory of Zoonosis Research, Fujian Center for Disease Control and Prevention, No. 76 Jintai Road, Gulou District, Fuzhou, 350001, Fujian, China.
Jiming ZhangDepartment of Infection Disease, Huashan Hospital Fudan University, No. 12 Wulumuqi Middle Road, Shanghai, 200040, China.
Xibin ZhuangDepartment of Respiratory Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China. zxbqz@163.com.
Zhijun SuDepartment of Infection Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China. su2366@sina.com.
Yongjun ZhouInstitute of Bioengineering and Biotechnology, College of Life Sciences and Chemistry, Minnan Science and Technology University, Quanzhou, 362000, China. zyj@mku.edu.cn.
Xueping YuDepartment of Infection Disease, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China. xpyu15@fudan.edu.cn.
Fujian Medical University · CNHuashan Hospital · CNMinnan University of Science and Technology · CN

Funding

Major Health Research Project of Fujian Province 2021ZD01001Science and Technology Innovation Joint Project of Fujian province 2019Y9048Scientific and Technological Development Project of Central Government shall guide local 2021L3018Young and middle-aged Talents Training Project of Fujian Provincial Health Commission 2020GGA076
6 · The paper itself

Abstract

Epidemiological and clinical data of patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant (BA.2) admitted to three designated hospitals in Quanzhou City, Fujian Province, China, were collected and analyzed. Overall, 2,541 patients infected with BA.2, comprising 1,060 asymptomatic, 1,287 mild, and 194 moderate infections, were enrolled. The percentage of moderate infections was higher in patients aged ≥ 60 years than in those aged < 18 years and 18-59 years. The median hospitalization duration was 17 days. Among the 2,541 patients, 43.52% had a clear history of close contact. The vaccination rate was 87.92%, and the percentage of asymptomatic infections was higher in vaccinated than in unvaccinated patients. Moreover, patients with underlying diseases, including hypertension and diabetes mellitus, had more moderate infections than those without underlying diseases. The three most common clinical manifestations were fever, dry cough, and sore throat. The albumin-to-globulin (A/G) ratio and lymphocyte count decreased in cases with mild and moderate infections, while procalcitonin, erythrocyte sedimentation rate, interleukin-6, D-dimer, and C4 levels increased. Advanced age, non-vaccination, and underlying comorbid diseases were high-risk factors for disease progression in patients. However, dynamic monitoring of blood routine parameters, A/G ratio, and inflammatory indicators facilitated the prediction of disease progression.

Indexed as

COVID-19SARS-CoV-2ChinaDisease ProgressionHumansRetrospective Studies

Identifiers

PMID38092887
PMCPMC10719353
OpenAlexW4389686047

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.