Evidence map›Paper›PMID 38092388›Full record

ArticleEnvironmental health and preventive medicine2023

Copper-induced diurnal hepatic toxicity is associated with Cry2 and Per1 in mice.

Sarah Tominaga, Hiroki Yoshioka, Satoshi Yokota, Yosuke Tsukiboshi, Masumi Suzui, Makoto Nagai, Hirokazu Hara, Tohru Maeda, Nobuhiko Miura

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental health and preventive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Sarah TominagaCollege of Pharmacy, Kinjo Gakuin University.
Hiroki YoshiokaFaculty of Pharmacy, Gifu University of Medical Science.ORCID http://orcid.org/0000-0002-0977-434X
Satoshi YokotaDivision of Cellular and Molecular Toxicology, Center for Biological Safety and Research, National Institute of Health Sciences.
Yosuke TsukiboshiFaculty of Pharmacy, Gifu University of Medical Science.
Masumi SuzuiDepartment of Neurotoxicology, Nagoya City University Graduate School of Medical Sciences.
Makoto NagaiGraduate School of Health and Medicine, Gifu University of Medical Science.
Hirokazu HaraLaboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University.
Tohru MaedaCollege of Pharmacy, Kinjo Gakuin University.
Nobuhiko MiuraDepartment of Health Science, Yokohama University of Pharmacy.
Gifu University of Medical Science · JPKinjo Gakuin University · JPGifu Pharmaceutical University · JPNagoya City University · JPYokohama University of Pharmacy · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to investigate diurnal variations in copper-induced hepatic toxicity and the molecular mechanisms underlying this chronotoxicity.

methodsMale C57BL/6J mice were intraperitoneally injected with copper chloride (CuCl

resultsRepeated CuCl

conclusionThese results suggest that CuCl

Indexed as

CopperTranscription FactorsAnimalsCircadian RhythmCryptochromesLiverMaleMiceMice, Inbred C57BLMice, Inbred StrainsPeriod Circadian ProteinsCopperCry2 protein, mouseCryptochromesPer1 protein, mousePeriod Circadian ProteinsTranscription FactorsChronotoxicityCopperHepatotoxicity

Identifiers

PMID38092388
PMCPMC10739358
OpenAlexW4389634190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.