Evidence map›Paper›PMID 38092148›Full record

ArticleThe Journal of biological chemistry2024

Global RNA modifications to the MALAT1 triple helix differentially affect thermostability and weaken binding to METTL16.

Mika J Schievelbein, Carlos Resende, Madeline M Glennon, Matthew Kerosky, Jessica A Brown

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. METTL16-mBMC biology · 2026
    Article
  4. RNA Triple Helices: From Structures and Mechanisms to Therapeutic Targets.International journal of biological sciences · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mika J SchievelbeinDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA.
Carlos ResendeDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA.
Madeline M GlennonDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA.
Matthew KeroskyDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA.
Jessica A BrownDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA. Electronic address: jbrown33@nd.edu.
University of Notre Dame · US

Funding

Chemistry-Biochemistry-Biology Training Program at Notre DameT32GM075762 · NIGMS · UNIVERSITY OF NOTRE DAME · PI CHANG, MAYLAND F, MOBASHERY, SHAHRIAR · 2007 to 2021
$3.7M
Characterization of a Model System to Advance Triple-Stranded RNA BiologyR35GM133696 · NIGMS · UNIVERSITY OF NOTRE DAME · PI BROWN, JESSICA ANN · 2019 to 2023
$1.9M
Chemistry-Biochemistry-Biology Interface (CBBI) Program at Notre DameT32GM145773 · NIGMS · UNIVERSITY OF NOTRE DAME · PI Christian Corey Melander · 2022 to 2026
$1.5M
NIGMS NIH HHS R35 GM133696NIGMS NIH HHS T32 GM075762NIGMS NIH HHS T32 GM145773
6 · The paper itself

Abstract

Therapeutic mRNAs are generated using modified nucleotides, namely N

Indexed as

RNARNA, Long NoncodingMethyltransferasesNucleic Acid ConformationNucleotidesPseudouridineMethyltransferasesNucleotidesPseudouridineRNARNA, Long Noncodinglong noncoding RNAMALAT1METTL16mRNARNA methylationRNA methyltransferaseRNA modificationRNA–protein interactionRNA structureRNA triple helix

Identifiers

PMID38092148
PMCPMC10805700
OpenAlexW4389537897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.