Evidence map›Paper›PMID 38091963›Full record

ArticleMolecular biology and evolution2023

Ursa: A Comprehensive Multiomics Toolbox for High-Throughput Single-Cell Analysis.

Lu Pan, Tian Mou, Yue Huang, Weifeng Hong, Min Yu, Xuexin Li

Open access · goldAbstract read
In one paragraph

Article in Molecular biology and evolution, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Lu PanInstitute of Environmental Medicine, Karolinska Institutet, Solna 171 65, Sweden.ORCID 0000-0001-7467-6992
Tian MouSchool of Biomedical Engineering, Shenzhen University, Shenzhen, Guangdong 518060, China.
Yue HuangDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna 171 65, Sweden.
Weifeng HongDepartment of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.ORCID 0000-0001-6640-2537
Min YuDepartment of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong 510515, China.ORCID 0000-0003-1875-740X
Xuexin LiDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna 171 65, Sweden.ORCID 0000-0001-5824-9720
Karolinska Institutet · SEGuangdong Academy of Medical Sciences · CNShenzhen University · CNSun Yat-sen University · CN

Funding

Karolinska Institute Network Medicine Global Alliance Collaborative
6 · The paper itself

Abstract

The burgeoning amount of single-cell data has been accompanied by revolutionary changes to computational methods to map, quantify, and analyze the outputs of these cutting-edge technologies. Many are still unable to reap the benefits of these advancements due to the lack of bioinformatics expertise. To address this issue, we present Ursa, an automated single-cell multiomics R package containing 6 automated single-cell omics and spatial transcriptomics workflows. Ursa allows scientists to carry out post-quantification single or multiomics analyses in genomics, transcriptomics, epigenetics, proteomics, and immunomics at the single-cell level. It serves as a 1-stop analytic solution by providing users with outcomes to quality control assessments, multidimensional analyses such as dimension reduction and clustering, and extended analyses such as pseudotime trajectory and gene-set enrichment analyses. Ursa aims bridge the gap between those with bioinformatics expertise and those without by providing an easy-to-use bioinformatics package for scientists in hoping to accelerate their research potential. Ursa is freely available at https://github.com/singlecellomics/ursa.

Indexed as

MultiomicsSoftwareComputational BiologyGenomicsSingle-Cell Analysisanalysis workflowmultimodal analysismultiomicssingle-cell

Identifiers

PMID38091963
PMCPMC10752348
OpenAlexW4389799786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.