ArticleEcotoxicology and environmental safety2024
Ambient ozone pollution impairs glucose homeostasis and contributes to renal function decline: Population-based evidence.
Article in Ecotoxicology and environmental safety, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Joint Associations of Residential Ambient PMNutrients · 2026Article
- Atmospheric stressors and kidney diseases.Nature reviews. Nephrology · 2026Review
- Association of long-term exposure to air pollution with the risk of new-onset pain among middle-aged and older people: a cohort study in China.Clinical rheumatology · 2026Article
- Air Pollution, Kidney Injury, and Green Nephrology-Thinking About Its Association and Causation.Journal of clinical medicine · 2025Review
- The Exposome and the Kidney: A Silent Dialogue Shaping Chronic Kidney Disease.Journal of xenobiotics · 2025Review
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Authors and funding
9 authors.
Funding
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Abstract
Particulate matter pollution could increase the risk of kidney disease, while evidence for ozone exposure is less well-established. Here, we aimed to evaluate the effect of ozone pollution on renal function and explore mechanisms. We first conducted a cross-sectional study based on Wuhan Chronic Disease Cohort Study baseline information. We recruited 2699 eligible participants, estimated their residential ozone concentrations, collected fasting peripheral blood samples for biochemical analysis and calculated the estimated glomerular filtration rate (eGFR). The linear regression model was applied to evaluate the long-term association between ozone pollution and eGFR. Then, we recruited another 70 volunteers as a panel with 8 rounds follow-up visits. We calculated the eGFR and measured fasting blood glucose and lipid levels. The linear mixed-effect model along with mediation analysis were performed to confirm the short-term association and explore potential mechanisms, respectively. For the long-term association, a 10.95 μg/m
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