Evidence map›Paper›PMID 38091601›Full record

ArticleBiochemistry2024

Mutational Analysis of the Nitrogenase Carbon Monoxide Protective Protein CowN Reveals That a Conserved C-Terminal Glutamic Acid Residue Is Necessary for Its Activity.

Dustin L Willard, Joshuah J Arellano, Mitch Underdahl, Terrence M Lee, Avinash S Ramaswamy, Gabriella Fumes, Agatha Kliman, Emily Y Wong, Cedric P Owens

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dustin L WillardDepartment of Chemistry and Biochemistry, Schmid College, Chapman University, Orange, California 92866, United States.
Joshuah J ArellanoDepartment of Chemistry and Biochemistry, Schmid College, Chapman University, Orange, California 92866, United States.
Mitch UnderdahlDepartment of Chemistry and Biochemistry, Schmid College, Chapman University, Orange, California 92866, United States.ORCID 0009-0008-7263-8368
Terrence M LeeDepartment of Chemistry and Biochemistry, Schmid College, Chapman University, Orange, California 92866, United States.
Avinash S RamaswamyDepartment of Chemistry and Biochemistry, Schmid College, Chapman University, Orange, California 92866, United States.
Gabriella FumesDepartment of Chemistry and Biochemistry, Schmid College, Chapman University, Orange, California 92866, United States.
Agatha KlimanDepartment of Chemistry and Biochemistry, Schmid College, Chapman University, Orange, California 92866, United States.
Emily Y WongDepartment of Chemistry and Biochemistry, Schmid College, Chapman University, Orange, California 92866, United States.ORCID 0009-0007-6954-2974
Cedric P OwensDepartment of Chemistry and Biochemistry, Schmid College, Chapman University, Orange, California 92866, United States.ORCID 0000-0002-8102-8181
Chapman University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitrogenase is the only enzyme that catalyzes the reduction of nitrogen gas into ammonia. Nitrogenase is tightly inhibited by the environmental gas carbon monoxide (CO). Many nitrogen fixing bacteria protect nitrogenase from CO inhibition using the protective protein CowN. This work demonstrates that a conserved glutamic acid residue near the C-terminus of

Indexed as

Glutamic AcidNitrogenaseCarbon MonoxideCarbon MonoxideGlutamic AcidNitrogenase

Identifiers

PMID38091601
PMCPMC10765410
OpenAlexW4389660721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.