Evidence map›Paper›PMID 38091383›Full record

ReviewRheumatology advances in practice2023

Current and future advances in practice: a practical approach to the diagnosis and management of primary central nervous system vasculitis.

Mats Junek, Kanjana S Perera, Matthew Kiczek, Rula A Hajj-Ali

Open access · goldAbstract readReview
In one paragraph

Review in Rheumatology advances in practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Intracranial GCA: a comprehensive systematic review.Rheumatology (Oxford, England) · 2025
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Advancing Knowledge in CNS Vasculitis.Neurology(R) neuroimmunology & neuroinflammation · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Mats JunekDepartment of Medicine, Division of Rheumatology, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0001-8416-3955
Kanjana S PereraDepartment of Medicine, Division of Neurology, McMaster University, Hamilton Health Sciences, Hamilton, ON, Canada.
Matthew KiczekDepartment of Rheumatic and Immunologic Disease, Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, USA.ORCID https://orcid.org/0000-0003-1729-5389
Rula A Hajj-AliDepartment of Neuroradiology, Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.
Cleveland Clinic · USHamilton Health Sciences · CAMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary CNS vasculitis (CNSV) is a rare, idiopathic autoimmune disease that, if untreated, can cause significant morbidity and mortality. It is a challenging diagnosis due to multiple mimics that can be difficult to differentiate, given that the CNS is an immunologically privileged and structurally isolated space. As such, diagnosis requires comprehensive multimodal investigations. Usually, a brain biopsy is required to confirm the diagnosis. Treatment of CNSV involves aggressive immunosuppression, but relapses and morbidity remain common. This expert review provides the reader with a deeper understanding of presentations of CNSV and the multiple parallel diagnostic pathways that are required to diagnose CNSV (and recognize its mimics), highlights the important knowledge gaps that exist in the disease and also highlights how we might be able to care for these patients better in the future.

Indexed as

brain biopsycentral nervous systemcollaborative careneuroradiologyvasculitis

Identifiers

PMID38091383
PMCPMC10712448
OpenAlexW4388975774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.