Evidence map›Paper›PMID 38091064›Full record

ArticleAbdominal radiology (New York)2024

Automated detection of incidental abdominal aortic aneurysms on computed tomography.

Devina Chatterjee, Thomas C Shen, Pritam Mukherjee, Sungwon Lee, John W Garrett, Nicholas Zacharias, Perry J Pickhardt, Ronald M Summers

Abstract read
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In one paragraph

Article in Abdominal radiology (New York), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Devina ChatterjeeRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892-1182, USA.
Thomas C ShenRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892-1182, USA.
Pritam MukherjeeRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892-1182, USA.
Sungwon LeeRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892-1182, USA.
John W GarrettDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA.
Nicholas ZachariasDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA.
Perry J Pickhardt *Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53726, USA.
Ronald M Summers *Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 20892-1182, USA. rms@nih.gov.ORCID http://orcid.org/0000-0001-8081-7376
National Institutes of Health Clinical Center · USUniversity of Wisconsin–Madison · US

Funding

Computer Aided Detection for CT ColonographyZ01CL040003 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2003 to 2008
$368k
Computer Aided Detection for Radiologic ImagesZ01CL040004 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2003 to 2008
$41k
Computer Aided Detection for CT ColonographyZIACL040003 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2009 to 2025
$0k
Intramural NIH HHS Z01 CL040003Intramural NIH HHS Z01 CL040004
6 · The paper itself

Abstract

purposeTo detect and assess abdominal aortic aneurysms (AAAs) on CT in a large asymptomatic adult patient population using fully-automated deep learning software. MATERIALS AND

methodsThe abdominal aorta was segmented using a fully-automated deep learning model trained on 66 manually-segmented abdominal CT scans from two datasets. The axial diameters of the segmented aorta were extracted to detect the presence of AAAs-maximum axial aortic diameter greater than 3 cm were labeled as AAA positive. The trained system was then externally-validated on CT colonography scans of 9172 asymptomatic outpatients (mean age, 57 years) referred for colorectal cancer screening. Using a previously-validated automated calcified atherosclerotic plaque detector, we correlated abdominal aortic Agatston and volume scores with the presence of AAA.

resultsThe deep learning software detected AAA on the external validation dataset with a sensitivity, specificity, and AUC of 96%, (95% CI 89%, 100%), 96% (96%, 97%), and 99% (98%, 99%) respectively. The Agatston and volume scores of reported AAA-positive cases were statistically significantly greater than those of reported AAA-negative cases (p < 0.0001). Using plaque alone as a AAA detector, at a threshold Agatston score of 2871, the sensitivity and specificity were 84% (73%, 94%) and 87% (86%, 87%), respectively.

conclusionFully-automated detection and assessment of AAA on CT is feasible and accurate. There was a strong statistical association between the presence of AAA and the quantity of abdominal aortic calcified atherosclerotic plaque.

Indexed as

Aortic Aneurysm, AbdominalPlaque, AtheroscleroticAdultAorta, AbdominalHumansMiddle AgedSensitivity and SpecificityTomography, X-Ray ComputedAbdominal aortaAgatston scoreAtherosclerotic calcificationCTDeep learning

Identifiers

PMID38091064
OpenAlexW4389681973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.