Evidence map›Paper›PMID 38090355›Full record

ReviewApplied biosafety : journal of the American Biological Safety Association2023

The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory-Foot and Mouth Disease Virus.

Stuart D Blacksell, Sandhya Dhawan, Marina Kusumoto, Kim Khanh Le, Kathrin Summermatter, Joseph O'Keefe, Joseph Kozlovac, Salama Suhail Almuhairi, Indrawati Sendow, Christina M Scheel and 6 more

Abstract readReview
In one paragraph

Review in Applied biosafety : journal of the American Biological Safety Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Findings and Recommendations of the RAV3N Applied Biorisk and Biosafety Gap Assessment Workshop.Applied biosafety : journal of the American Biological Safety Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Stuart D BlacksellMahidol-Oxford Tropical Research Medicine Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Sandhya DhawanMahidol-Oxford Tropical Research Medicine Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Marina KusumotoMahidol-Oxford Tropical Research Medicine Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Kim Khanh LeMahidol-Oxford Tropical Research Medicine Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Kathrin SummermatterInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0001-5519-5966
Joseph O'KeefeMinistry for Primary Industries, Wellington, New Zealand.
Joseph KozlovacUnited States Department of Agriculture, Agricultural Research Service, Beltsville, Maryland, USA.
Salama Suhail AlmuhairiAbu Dhabi Agriculture and Food Safety Authority, Abu Dhabi, United Arab Emirates.
Indrawati SendowIndonesian Research Center for Veterinary Science, Bogor, Indonesia.
Christina M ScheelWHO Collaborating Center for Biosafety and Biosecurity, Office of the Associate Director for Laboratory Science, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Anthony AhumibeNigeria Centre for Disease Control and Prevention, Abuja, Nigeria.ORCID https://orcid.org/0000-0002-4651-4424
Zibusiso M MasukuNational Institute for Communicable Diseases of the National Health Laboratory Services, Johannesburg, South Africa.
Allan M BennettUK Health Security Agency, Porton Down, United Kingdom.
Kazunobu KojimaDepartment of Epidemic and Pandemic Preparedness and Prevention World Health Organization (WHO), Geneva, Switzerland.
David R HarperThe Royal Institute of International Affairs, London, United Kingdom.
Keith HamiltonWorld Organisation for Animal Health (OIE), Paris, France.

Funding

World Health Organization 001
6 · The paper itself

Abstract

Introduction: Foot and mouth disease (FMD) is a highly contagious infection of cloven-hoofed animals. The Biosafety Research Road Map reviewed scientific literature regarding the foot and mouth disease virus (FMDV). This project aims to identify gaps in the data required to conduct evidence-based biorisk assessments, as described by Blacksell et al., and strengthen control measures appropriate for local and national laboratories. Methods: A literature search was conducted to identify potential gaps in biosafety and focused on five main sections: the route of inoculation/modes of transmission, infectious dose, laboratory-acquired infections, containment releases, and disinfection and decontamination strategies. Results: The available data regarding biosafety knowledge gaps and existing evidence have been collated. Some gaps include the need for more scientific data that identify the specific safety contribution of engineering controls, support requirements for showering out after in vitro laboratory work, and whether a 3- to 5-day quarantine period should be applied to individuals conducting in vitro versus in vivo work. Addressing these gaps will contribute to the remediation and improvement of biosafety and biosecurity systems when working with FMDV.

Indexed as

biorisk managementbiosafety evidencebiosafety knowledge gap analysisfoot and mouth diseasepathogen characteristics

Identifiers

PMID38090355
PMCPMC10712356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.