Evidence map›Paper›PMID 38090319›Full record

ArticleJournal of thoracic disease2023

A signature of five 7-methylguanosine-related genes is a prognostic marker for lung squamous cell carcinoma.

Wensheng Liu, Ying Wang, Paola Ulivi, Simona Tavolari, Syed A A Rizvi, Enrico Capobianco, Alfons Navarro, Yongjun Zhang

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The role of m5C, m1A and m7G modifications in tumors of urinary system.Frontiers in cell and developmental biology · 2025
    Review
  5. Decoding the role of tRNA modifications in cancer progression.Current opinion in genetics & development · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Wensheng LiuCritical Care Medicine Department, Zhejiang Cancer Hospital, Hangzhou, China.
Ying WangGynecological Oncology Department, Zhejiang Cancer Hospital, Hangzhou, China.
Paola UliviBiosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" (IRST), Meldola, Italy.
Simona TavolariMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Syed A A RizviCollege of Biomedical Sciences, Larkin University, Miami, FL, USA.
Enrico CapobiancoDepartment of Computational Science, The Jackson Laboratory, Farmington, CT, USA.
Alfons NavarroMolecular Oncology and Embryology Laboratory, Department of Surgery and Surgical Specializations, Human Anatomy Unit, Faculty of Medicine and Health Sciences, University of Barcelona (UB), Barcelona, Spain.
Yongjun ZhangIntegration of Traditional Chinese and Western Medicine Department, Zhejiang Cancer Hospital, Hangzhou, China.
Zhejiang Cancer Hospital · CNAzienda USL di Bologna · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITJackson Laboratory · USLarkin University · USUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: N Methods: Twenty-nine m7G-related genes were selected for the analysis in the LSCC cohort of the Cancer Genome Atlas (TCGA). Univariate, multivariate, and Kaplan-Meier analyses were used to evaluate the predictive value of risk model developed with m7G signature for overall survival (OS).. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses of differentially expressed genes (DEGs) were performed for high- and low-risk LSCC groups. Results: We identified 17 differentially expressed m7G methylation-related genes in LSCC versus normal tissues. The expression of five m7G-related genes ( Conclusions: We developed a novel m7G-related gene signature that can be of great utility to predict the prognosis for patients with LSCC.

Indexed as

biomarkerN7-methylguanosine (m7G)Non-small cell lung cancer (NSCLC)prognosisThe Cancer Genome Atlas (TCGA)

Identifiers

PMID38090319
PMCPMC10713324
OpenAlexW4389100809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.