Evidence map›Paper›PMID 38090082›Full record

ReviewRSC advances2023

Advances in Aβ imaging probes: a comprehensive study of radiolabelled 1,3-diaryl-2-propen-1-ones for Alzheimer's disease: a review.

Sudeep Dhillon, Mayank Kinger, Priyanka Rani, Mamta Chahal, Ginna Kumari, Deepak Kumar Aneja, Sang Wook Kim, Eunseok Choi, Sushil Kumar

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Sudeep DhillonDepartment of Chemistry, Chaudhary Bansi Lal University Bhiwani 127031 Haryana India drmayankkinger@cblu.ac.in.ORCID https://orcid.org/0009-0001-3463-0030
Mayank KingerDepartment of Chemistry, Chaudhary Bansi Lal University Bhiwani 127031 Haryana India drmayankkinger@cblu.ac.in.ORCID https://orcid.org/0000-0002-4269-0834
Priyanka RaniDepartment of Chemistry, Chaudhary Bansi Lal University Bhiwani 127031 Haryana India drmayankkinger@cblu.ac.in.ORCID https://orcid.org/0009-0003-0852-6170
Mamta ChahalDepartment of Chemistry, Chaudhary Bansi Lal University Bhiwani 127031 Haryana India drmayankkinger@cblu.ac.in.ORCID https://orcid.org/0009-0003-3170-289X
Ginna KumariDepartment of Chemistry, Chaudhary Bansi Lal University Bhiwani 127031 Haryana India drmayankkinger@cblu.ac.in.ORCID https://orcid.org/0009-0007-2677-6260
Deepak Kumar AnejaDepartment of Chemistry, Chaudhary Bansi Lal University Bhiwani 127031 Haryana India drmayankkinger@cblu.ac.in.ORCID https://orcid.org/0000-0003-3901-0487
Sang Wook KimDepartment of Advanced Materials Chemistry, Dongguk University Gyeongju 38066 Republic of Korea.
Eunseok ChoiDepartment of Advanced Materials Chemistry, Dongguk University Gyeongju 38066 Republic of Korea.
Sushil KumarBiozenta Lifescience Pvt. Ltd Ind. Area Tahliwal Una HP 174303 India.ORCID https://orcid.org/0009-0002-8932-5110
Chaudhary Devi Lal University · INDongguk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a formidable neurodegenerative disorder characterized by cognitive decline, memory impairment and inability to perform everyday tasks. In the pursuit of innovative diagnostic and therapeutic strategies, the synthesis and application of radiolabelled compounds have garnered significant attention. This review delves into the synthesis and biological significance of radiolabelled 1,3-diaryl-2-propen-1-ones, commonly known as chalcones, as Aβ imaging probes for AD. These versatile chalcone derivatives have demonstrated noteworthy potential as radiotracers for visualizing Aβ imaging probes, which are hallmark pathologies of AD. This review encompasses an exploration of chalcone synthesis

Identifiers

PMID38090082
PMCPMC10712011
OpenAlexW4389561042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.