ReviewMediastinum (Hong Kong, China)2023
Overview of malignant central airway obstruction.
Review in Mediastinum (Hong Kong, China), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Microdebrider - Assisted management of central airway obstruction via rigid bronchoscopy: A preliminary study on safety and efficacy.Lung India : official organ of Indian Chest Society · 2026Article
- Carinal Squamous Cell Carcinoma Causing Progressive Central Airway Obstruction: CT, FDG PET/CT, Bronchoscopic Pre- and Post-Debulking, and Pathologic Correlation.Case reports in radiology · 2026Article
- Article
- Narrative review of malignant central airway obstruction: management updates.Journal of thoracic disease · 2025Review
- Fire: argon plasma coagulation, diathermy and laser.Breathe (Sheffield, England) · 2025Review
- Endobronchial lipoma: a rare cause of bronchial obstruction-case report and literature review.Discover oncology · 2025Article
- Three-dimensional tracheo-bronchial reconstruction to plan endoscopic stent insertion for malignant upper airway stenosis.Interdisciplinary cardiovascular and thoracic surgery · 2025Observational
- Long-Term Outcomes of Interventional Bronchoscopy for Central Airway Obstruction in a Single-Center Retrospective Study: A Subgroup Analysis of Malignant and Benign Lesions.Journal of clinical medicine · 2025Article
- Corticosteroids in lung cancer.Frontiers in drug safety and regulation · 2025Review
- Central airway carcinoid tumor mimicking chronic asthma and necessitating pneumonectomy: A case report.International journal of surgery case reports · 2024Article
- Advancing Postoperative Pain Management in Oral Cancer Patients: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Effective Differences between 2D and 3D Planned Brachytherapy in Lung Cancer: An Institutional Retrospective Study.Medicina (Kaunas, Lithuania) · 2024Article
- External Beam Radiotherapy for Malignant Central Airway Obstruction in a Remote Rural Patient: A Case Study.Case reports in oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant central airway obstruction (MCAO) impacts many patients with advanced primary lung cancers and metastatic disease to the thorax and may cause substantial symptoms and functional limitations in those affected. Making the diagnosis may be challenging as symptoms are often non-specific but identification is improved with a heightened level of suspicion and newer thoracic imaging modalities. Bronchoscopy plays a crucial role in the diagnosis and management of MCAO and therapeutic interventions may be lifesaving and result in palliation of symptoms. This may ultimately improve a patient's candidacy to receive additional systemic or local cancer therapies or potential tumor resection. After initial stabilization, it is important that patients with MCAO undergo prompt evaluation and treatment. Multiple bronchoscopic instruments are available for management depending on tumor characteristics, location of the obstruction, and viability of distal airways, and may be utilized in combination during therapeutic procedures. These modalities include dilation, endobronchial stent placement, thermal and non-thermal ablation, mechanical debulking, and novel endobronchial therapies. While these procedures are not without risk, there is ample evidence showing improvements in patient symptoms, quality of life, and survival following therapeutic bronchoscopy. This review article provides a general overview of the diagnosis and management of MCAO with a focus on bronchoscopic interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.