ArticleFrontiers in neuroscience2023
High-beta oscillations at EEG resting state and hyperconnectivity of pain circuitry in fibromyalgia: an exploratory cross-sectional study.
Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- A systematic review of brain health in adults with chronic pain.Anaesthesia · 2026Pooled it
- Management of Juvenile Fibromyalgia: A Level I Evidence-Based Systematic Review.Medical sciences (Basel, Switzerland) · 2025Pooled it
- Seed-based resting-state connectivity as a neurosignature in fibromyalgia and depression: a narrative systematic review.Frontiers in human neuroscience · 2025Pooled it
- Trial
- Electroencephalography research in neuropathic pain (Review).Molecular medicine reports · 2026Review
- Chronic pain and oscillatory neuroplasticity: Review on impaired compensatory network responses in resting-state electroencephalography.Brain network disorders · 2026Article
- Multivariate Pattern Analysis Identifies Potential Intertrial Resting-State EEG Biomarkers in Fibromyalgia.The European journal of neuroscience · 2026Article
- Exploratory EEG correlates of sensory and affective pain dimensions in patients with chronic widespread pain.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Normative Modeling of EEG Complexity Reveals Cortical Rigidity Associated with Pain Severity in Chronic Pain.Journal of pain research · 2026Article
- Exploring Neural Signaling Patterns and Their Physiological Origins in Fibromyalgia by Means of Functional MRI Guided by a Review of the Literature.Brain sciences · 2025Article
- Article
- The characteristics of brain function alterations in patients with chronic prostatitis/chronic pelvic pain syndrome across varying symptom severities evaluated by NIH-CPSI.Frontiers in neuroscience · 2025Article
- EEG connectivity features associated with fibromyalgia revealed by machine learning.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Exploring Electrophysiological Responses to Hypnosis in Patients with Fibromyalgia.Brain sciences · 2024Article
- The Role of the Insula in Chronic Pain and Associated Structural Changes: An Integrative Review.Cureus · 2024Review
- Resting-state electroencephalography delta and theta bands as compensatory oscillations in chronic neuropathic pain: a secondary data analysis.Brain network and modulationArticle
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Electroencephalography (EEG) has identified neural activity in specific brain regions as a potential indicator of the neural signature of chronic pain. This study compared the lagged coherence connectivity between regions of interest (ROIs) associated with the pain connectome in women with fibromyalgia (FM) and healthy women (HC). Methods: We evaluated 64 participants (49 FM and 15 HC) during resting-state EEG sessions under both eyes open (EO) and eyes closed (EC) conditions. In addition to EEG measurements, we assessed clinical and psychological symptoms and serum levels of brain-derived neurotrophic factor (BDNF). The connectivity between eight ROIs was computed across eight different EEG frequencies. Results: The FM group demonstrated increased connectivity between the left dorsolateral prefrontal cortex (DLPFC) and right anterior cingulate cortex (ACC), specifically in the beta-3 frequency band ( Conclusion: These findings indicate that increased connectivity between different pain processing circuits, particularly in the beta-3 frequency band during rest, may serve as neural biomarkers for the chronic pain brain signature associated with neuroplasticity and the severity of FM symptoms.
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Registered trials
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