Evidence map›Paper›PMID 38089879›Full record

ArticleFrontiers in medicine2023

The median effective dose of propofol combined with butorphanol during artificial abortion: a randomized controlled trial.

Yuling Zheng, Jinping Huang, Ying Mai, Xiaoling Li, Zhongqi Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuling Zheng *Department of Anesthesiology, The Affiliated Shunde Hospital of Jinan University, Foshan, China.
Jinping Huang *Department of Anesthesiology, The Seventh Affiliated Hospital of Southern Medical University, Foshan, China.
Ying MaiDepartment of Anesthesiology, The Affiliated Shunde Hospital of Jinan University, Foshan, China.
Xiaoling LiDepartment of Anesthesiology, The Affiliated Shunde Hospital of Jinan University, Foshan, China.
Zhongqi ZhangDepartment of Anesthesiology, The Affiliated Shunde Hospital of Jinan University, Foshan, China.
Jinan University · CNThird Affiliated Hospital of Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Propofol-opioids are the most common drug combination and can reduce the dose of propofol and the incidence of adverse events in painless artificial abortion. We hypothesized that butorphanol may reduce the median effective dose (ED Methods: This was a randomized, double-blind, controlled study. A total of 54 female patients, who had ASA I or II, aged 18-49 years, undergoing painless artificial abortion, were randomly assigned into two groups, namely, Group P (propofol) and Group PB (propofol plus 10 μg/kg butorphanol). According to the pre-experiment, the initial dose of propofol for the P and PB groups was 3 and 2.5 mg/kg, respectively, with a dose gradient of 0.25 mg/kg. The ED Results: There were 25 and 29 patients in the P and PB groups, respectively. The ED Conclusion: Combination of propofol with 10 μg/kg butorphanol reduced the ED Clinical trial registration: https://www.chictr.org.cn/showproj.html?proj=166610, identifier: ChiCTR2200059795.

Indexed as

butorphanolmedian effective dosepainless abortionpropofolup-and-down method

Identifiers

PMID38089879
PMCPMC10711101
OpenAlexW4389054282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.