ArticleEClinicalMedicine2023
Developing consensus on core outcome sets of domains for acute, the transition from acute to chronic, recurrent/episodic, and chronic pain: results of the INTEGRATE-pain Delphi process.
Article in EClinicalMedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A systematic review of physical activity-based interventions to prevent or reduce chronic post-surgical pain.Pain medicine (Malden, Mass.) · 2026Pooled it
- European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations.United European gastroenterology journal · 2026Guideline
- Postoperative Pain Management After Lumbar Discectomy. A Systematic Review With Meta-Analyses and Trial Sequential Analyses.European journal of pain (London, England) · 2026Pooled it
- Ketamine and other NMDA receptor antagonists for chronic pain.The Cochrane database of systematic reviews · 2025Pooled it
- The effect of intraoperative dexmedetomidine versus ketamine on postoperative pain in patients receiving a femoral nerve block for total knee arthroplasty: a randomized trial.BMC anesthesiology · 2025Trial
- Outcome-framework adherence in neuromodulation studies for chronic pain: evidence from a systematic gap map.Anaesthesia · 2026Article
- Improving Clinical Trial Design in Low Back Pain: Insights from Studies of Gabapentinoids.Pain and therapy · 2026Review
- [Endometriosis pain research in Germany : ENDO-PAIN and StEPP-UPP-two new research consortia on endometriosis pain].Schmerz (Berlin, Germany) · 2026Review
- [Postoperative pain and sex/gender-current findings of the past decade].Schmerz (Berlin, Germany) · 2026Article
- Cognitive-behavioural treatment for neck pain.The Cochrane database of systematic reviews · 2026Article
- Why pain biomarkers cannot replace the patient experience.Nature neuroscience · 2026Article
- Preliminary Benefits of In-Home Virtual Reality for Chronic Pain in Sickle Cell Disease: Pilot Randomized Trial.Biomedicines · 2026Article
- 1st Global Consensus for Clinical Guidelines: Identifying a Core Outcome Set for Implant Dentistry in Edentulous Maxilla Rehabilitation.Clinical oral implants research · 2026Article
- Review
- Response to De Paepe et al.Pain reports · 2025Article
- Capturing individual experiences: advancing core outcome sets in pain. Comment on Taylor et al. (2024).Pain reports · 2025Article
- Turning Patients' Open-Ended Narratives of Chronic Pain Into Quantitative Measures: Natural Language Processing Study.JMIR human factors · 2025Article
- Physician and patient perspectives on PROM implementation barriers in spine care and pain management: a mixed-methods assessment.BMJ open quality · 2025Article
- Pain intensity and prognosis of acute pancreatitis in an international, prospective study.The British journal of surgery · 2025Article
- The current state of digital manikins to support pain self-reporting: a systematic literature review.Pain reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pain is the leading cause of disability worldwide among adults and effective treatment options remain elusive. Data harmonization efforts, such as through core outcome sets (COS), could improve care by highlighting cross-cutting pain mechanisms and treatments. Existing pain-related COS often focus on specific conditions, which can hamper data harmonization across various pain states. Methods: Our objective was to develop four overarching COS of domains/subdomains (i.e., Findings: Domains in final COS were generally related to aspects of pain, quality of life, and physical function/activity limitations, with some differences among pain categories. This effort was the first to generate four separate, overarching COS to encourage international data harmonization within and across different pain categories. Interpretation: The adoption of the COS in research and clinical practice will facilitate comparisons and data integration around the world and across pain studies to optimize resources, expedite therapeutic discovery, and improve pain care. Funding: Innovative Medicines Initiative 2 Join Undertaking; European Union Horizon 2020 research innovation program, European Federation of Pharmaceutical Industries and Associations (EFPIA) provided funding for IMI-PainCare. RDT acknowledges grants from Esteve and TEVA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.