ArticleEClinicalMedicine2023
Early life exposures contributing to accelerated lung function decline in adulthood - a follow-up study of 11,000 adults from the general population.
Article in EClinicalMedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Normal age-related decline in forced vital capacity: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Regenerative therapeutics for chronic obstructive pulmonary disease.Pharmacological reviews · 2026Review
- Smoking exposures and mortality risk in individuals with idiopathic pulmonary fibrosis: a UK Biobank cohort study.Frontiers in public health · 2026Article
- Maternal smoking around birth and respiratory tract infection in adult offspring: A Mendelian randomization study.Tobacco induced diseases · 2026Article
- Childhood respiratory risk profiles associate with lung function and COPD among the old population.Annals of medicine · 2025Article
- Beyond genes: a clinician's guide to epigenetics.Breathe (Sheffield, England) · 2025Review
- Dietary patterns, nutrients, and risk of expiratory airflow limitation in children and adolescents.European journal of nutrition · 2025Article
- Respiratory health and chronic disease risks in residents of agricultural areas in Chiang Mai, Northern Thailand.PloS one · 2025Article
- Adult Outcomes of Childhood Wheezing Phenotypes Are Associated with Early-Life Factors.Journal of personalized medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 19 institutions in 14 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: We aimed to assess whether exposure to risk factors in early life from conception to puberty continue to contribute to lung function decline later in life by using a pooled cohort comprising approx. 11,000 adults followed for more than 20 years and with up to three lung function measurements. Methods: Participants (20-68 years) in the ECRHS and NFBC1966 cohort studies followed in the periods 1991-2013 and 1997-2013, respectively, were included. Mean annual decline in maximum forced expired volume in 1 s (FEV Findings: Decline in lung function was accelerated in participants with mothers that smoked during pregnancy (FEV Interpretation: Mothers' smoking during pregnancy, parental asthma and early menarche may contribute to a decline of FEV Funding: European Union's Horizon 2020; Research Council of Norway; Academy of Finland; University Hospital Oulu; European Regional Development Fund; Spanish Ministry of Science and Innovation; Generalitat de Catalunya.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.