Evidence map›Paper›PMID 38089821›Full record

ArticleFrontiers in cellular and infection microbiology2023

Berit Sletbakk Brusletto, Bernt Christian Hellerud, Reidun Øvstebø, Petter Brandtzaeg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Berit Sletbakk BruslettoDepartment of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
Bernt Christian HellerudInstitute of Immunology, Oslo University Hospital, Oslo, Norway.
Reidun ØvstebøDepartment of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
Petter BrandtzaegDepartment of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
Oslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Objective: 1) To explore the feasibility of measuring LPS levels in tissues from the large organs in patients with meningococcal septic shock and in a porcine meningococcal septic shock model. 2) To evaluate the extent of contamination of non-specific LPS during the preparation of tissue samples. Patients and methods: Plasma, serum, and fresh frozen (FF) tissue samples from the large organs of three patients with lethal meningococcal septic shock and two patients with lethal pneumococcal disease. Samples from a porcine meningococcal septic shock model were included. Frozen tissue samples were thawed, homogenized, and prepared for quantification of LPS by Pyrochrome Results: Conclusion: Our results suggest that LPS can be quantified in mammalian tissues by using the LAL assay.

Indexed as

Meningitis, MeningococcalMeningococcal InfectionsNeisseria meningitidisPneumococcal InfectionsSepsisShock, SepticAnimalsDNAHumansLipopolysaccharidesMammalsSwineDNALipopolysaccharidesLAL-assayLPS in tissue samplesLPS (lipopolysaccharide)meningococcal DNAmeningococcal septic shockmultiple organ failure - MOFNeisseria meningitidisporcine shock model

Identifiers

PMID38089821
PMCPMC10713808
OpenAlexW4389098207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.