Evidence map›Paper›PMID 38089743›Full record

ArticleToxicon: X2024

Snake venom cysteine-rich secretory protein from Mojave rattlesnake venom (Css-CRiSP) induces acute inflammatory responses on different experimental models.

Emelyn Salazar, Abcde Cirilo, Armando Reyes, Martha Barrientos, Jacob Galan, Elda E Sánchez, Montamas Suntravat

Open access · goldAbstract read
In one paragraph

Article in Toxicon: X, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Histopathological characterization of skin and muscle lesions induced by lionfish (The journal of venomous animals and toxins including tropical diseases · 2025
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Emelyn SalazarNational Natural Toxins Research Center, Texas A&M University-Kingsville, Kingsville, TX, USA.
Abcde CiriloNational Natural Toxins Research Center, Texas A&M University-Kingsville, Kingsville, TX, USA.
Armando ReyesNational Natural Toxins Research Center, Texas A&M University-Kingsville, Kingsville, TX, USA.
Martha BarrientosNational Natural Toxins Research Center, Texas A&M University-Kingsville, Kingsville, TX, USA.
Jacob GalanDepartment of Human Genetics, University of Texas Rio Grande Valley, Brownsville, TX, USA.
Elda E SánchezNational Natural Toxins Research Center, Texas A&M University-Kingsville, Kingsville, TX, USA.
Montamas SuntravatNational Natural Toxins Research Center, Texas A&M University-Kingsville, Kingsville, TX, USA.
Texas A&M University – Kingsville · USThe University of Texas Rio Grande Valley · US

Funding

Viper Resource Grant at Texas A&M University-KingsvilleP40OD010960 · OD · TEXAS A&M UNIVERSITY-KINGSVILLE · PI Elda E. Sanchez · 2012 to 2026
$9.2M
NIH HHS P40 OD010960
6 · The paper itself

Abstract

Snake venoms contain various molecules known for activating innate immunity and causing local effects associated with increased vascular permeability, such as vascular leakage and edema, common symptoms seen in snakebite envenomings. We have demonstrated that snake venom cysteine-rich secretory proteins (svCRiSPs) from North American pit vipers increase vascular permeability. This study aimed to explore the functional role of CRiSP isolated from Mojave rattlesnake (

Indexed as

CytokineEndothelial cellsInflammatory responseMojave rattlesnake (Crotalus scutulatus scutulatus)Monocyte-derived macrophages (MDM)Snake venom cysteine-rich secretory protein (svCRiSP)

Identifiers

PMID38089743
PMCPMC10713845
OpenAlexW4389454927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.