Evidence map›Paper›PMID 38088984›Full record

ArticleOpen forum infectious diseases2023

Evaluation of Dolutegravir- and Bictegravir-Based Antiretroviral Regimen Utilization in Patients who Cannot Take Medications by Mouth.

Megan LoFaso, Olivia Marchionda, Stephanie Bass, Heather Torbic, Caitlin Blackewicz, Andrea Pallotta

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Megan LoFasoDepartment of Pharmacy, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-6576-7021
Olivia MarchiondaDepartment of Pharmacy, Cleveland Clinic, Cleveland, Ohio, USA.
Stephanie BassDepartment of Pharmacy, Cleveland Clinic, Cleveland, Ohio, USA.
Heather TorbicDepartment of Pharmacy, Cleveland Clinic, Cleveland, Ohio, USA.
Caitlin BlackewiczDepartment of Infectious Diseases, Cleveland Clinic, Cleveland, Ohio, USA.
Andrea PallottaDepartment of Pharmacy, Cleveland Clinic, Cleveland, Ohio, USA.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A retrospective review of patients unable to take medications by mouth showed short interruptions of therapy for most patients. In a secondary analysis, our data showed maintenance and/or achievement of viral suppression for most patients. A retrospective review of intensive care patients unable to take antiretrovirals by mouth showed 56.6% of patients experiencing a transient interruption in therapy. Additionally, our case series further supports previous literature on crushing dolutegravir and bictegravir regimens to maintain and achieve viral suppression.

Indexed as

bictegravircrusheddolutegravirHIV

Identifiers

PMID38088984
PMCPMC10712287
OpenAlexW4388639062

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.