Evidence map›Paper›PMID 38088546›Full record

ArticleMicrobiology spectrum2024

Uncovering the diversity and distribution of biosynthetic gene clusters of prochlorosins and other putative RiPPs in marine

Patricia Arias-Orozco, Lu Zhou, Yunhai Yi, Rubén Cebrián, Oscar P Kuipers

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 3 countries.

Patricia Arias-OrozcoDepartment of Molecular Genetics, University of Groningen , Nijenborgh, Groningen, The Netherlands.ORCID 0000-0002-0771-6373
Lu ZhouDepartment of Molecular Genetics, University of Groningen , Nijenborgh, Groningen, The Netherlands.ORCID 0000-0001-6814-034X
Yunhai YiDepartment of Molecular Genetics, University of Groningen , Nijenborgh, Groningen, The Netherlands.ORCID 0000-0002-3516-6700
Rubén CebriánDepartment of Molecular Genetics, University of Groningen , Nijenborgh, Groningen, The Netherlands.ORCID 0000-0003-1575-1846
Oscar P KuipersDepartment of Molecular Genetics, University of Groningen , Nijenborgh, Groningen, The Netherlands.ORCID 0000-0001-5596-7735
University of Groningen · NL

Funding

Chinese Scholarship CouncilChinese Scholarsip CouncilEC | Horizon 2020 Framework Programme (H2020) 713482NWO NACTAR PROGRAM 16433
6 · The paper itself

Abstract

importanceGenome mining studies have revealed the remarkable combinatorial diversity of ribosomally synthesized and post-translationally modified peptides (RiPPs) in marine bacteria, including prochlorosins. However, mining strategies also prove valuable in investigating the genomic landscape of associated genes within biosynthetic gene cluster (BGC) specific to targeted RiPPs of interest. Our study contributes to the enrichment of knowledge regarding prochlorosin diversity. It offers insights into potential mechanisms involved in their biosynthesis and modification, such as hyper-modification, which may give rise to active lantibiotics. Additionally, our study uncovers putative novel promiscuous post-translational enzymes, thereby expanding the chemical space explored within the

Indexed as

SynechococcusGenomeGenomicsHumansMultigene FamilyPeptidesProtein Processing, Post-TranslationalPeptideslanthipeptidesprochlorosinsSynechococcussynechococsins

Identifiers

PMID38088546
PMCPMC10783134
OpenAlexW4389685950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.