Evidence map›Paper›PMID 38088542›Full record

ArticleMicrobiology spectrum2024

Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19.

Liuying Chen, Zhongwei Yin, Dan Zhou, Xin Li, Cheng Yu, Chang Luo, Yu Jin, Lei Zhang, Jun Song, Leo Rasche and 5 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Liuying Chen *Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Zhongwei Yin *Division of Cardiology, Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Dan ZhouDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Xin LiDepartment of Paediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Cheng YuUltrasonic Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Chang LuoDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Yu JinDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Lei ZhangDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Jun SongDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Leo RascheDepartment of Internal Medicine II, University Hospital Würzburg, Julius-Maximilian University of Würzburg , Würzburg, Germany.
Hermann EinseleDepartment of Internal Medicine II, University Hospital Würzburg, Julius-Maximilian University of Würzburg , Würzburg, Germany.
Lei TuDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Xiang ZhouDepartment of Internal Medicine II, University Hospital Würzburg, Julius-Maximilian University of Würzburg , Würzburg, Germany.ORCID 0000-0003-3885-0919
Tao BaiDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.ORCID 0000-0001-9697-8510
Xiaohua HouDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China.
Union Hospital · CNUniversity of Würzburg · DETongji Hospital · CN

Funding

Department of Science and Technology of Hubei Province () 2020BHB017, 2020FCA014| Natural Science Foundation of Hubei Province () 2021CFB450Wuhan Intellectual Property Bureau | Wuhan Science and Technology Project () 2022020801010462
6 · The paper itself

Abstract

importanceThe 2019 coronavirus disease (COVID-19) patients had a unique profile of gut bacteria. In this study, we characterized the intestinal bacteria in our COVID-19 cohorts and found that there was an increased incidence of severe cases in COVID-19 patients with decreased lymphocytes and increased neutrophils. Levels of lymphocytes and neutrophils and abundances of intestinal bacteria correlated with the severity of COVID-19.

Indexed as

COVID-19NeutrophilsHumansLymphocyte CountLymphocytesSARS-CoV-2bacteriaCOVID-19lymphocytesneutrophils

Identifiers

PMID38088542
PMCPMC10783053
OpenAlexW4389673392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.