Evidence map›Paper›PMID 38087860›Full record

ArticleHip international : the journal of clinical and experimental research on hip pathology and therapy2024

What is the most appropriate comparator group to use in assessing the performance of primary total hip prostheses within the community?

Khashayar Ghadirinejad, Stephen Graves, Richard de Steiger, Nicole Pratt, Lucian B Solomon, Mark Taylor, Reza Hashemi

Abstract readComparative Study
In one paragraph

Article in Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Khashayar GhadirinejadThe Medical Device Research Institute, College of Science and Engineering, Flinders University, Adelaide, SA, Australia.
Stephen GravesThe Australian Orthopaedic Association National Joint Replacement Registry, Adelaide, SA, Australia.
Richard de SteigerThe Australian Orthopaedic Association National Joint Replacement Registry, Adelaide, SA, Australia.
Nicole PrattQuality Use of Medicines and Pharmacy Research Centre, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia.
Lucian B SolomonCentre for Orthopaedic and Trauma Research, University of Adelaide, Adelaide, SA, Australia.
Mark TaylorThe Medical Device Research Institute, College of Science and Engineering, Flinders University, Adelaide, SA, Australia.
Reza HashemiThe Medical Device Research Institute, College of Science and Engineering, Flinders University, Adelaide, SA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are variations in the performance of individual prostheses used in hip replacements. Some of which have unexpectedly higher revision rates - outliers. The Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) has established a standardised multi-stage approach for identifying these devices. This is done by comparing the revision rates of individual prostheses to all other prostheses in class, with the exception of large head metal-on-metal (LHMoM) prostheses. However, improvements in device design and performance over time have required a need to reconsider the comparator group. This study aimed to identify a more specific comparator to better reflect contemporary surgical practice.

methodsThe time to first revision was estimated on the data of 413,417 primary total conventional hip replacements undertaken for osteoarthritis (OA) from 01 January 2003 to 31 December 2019. Survivorship analyses with stepwise exclusions were undertaken. The first exclusion was LHMoM, followed by other non-modern bearing surfaces (defined as all the bearing couples except metal or ceramic heads on cross-linked polyethylene and mixed ceramic-on-ceramic), and then devices with modular neck-stem design or used for specific purposes (incl. constrained, dual-mobility, and head size <28 mm). Lastly, all remaining prostheses previously identified as having a higher than anticipated rate of revision (HTARR) were also excluded.

resultsThese exclusions progressively reduced the cumulative percent revision (CPR) rate. The final comparator, which only includes satisfactory-performed prostheses of contemporary design and use, has a 10-year CPR of 4.30% (95% CI, 4.2-4.41) which is lower than 4.93% (95% CI, 4.84-5.02) for the current comparator used by the AOANJRR (all prostheses excluding LHMOM). Over the study period, 13 additional components were identified utilising the modified comparator.

conclusionsThe calculation of the comparator revision rate should be re-evaluated to include only modern prosthesis constructs to ensure that poorly performing prostheses are identified early.

Indexed as

Arthroplasty, Replacement, HipHip ProsthesisProsthesis DesignProsthesis FailureReoperationAgedAustraliaFemaleHumansMaleMiddle AgedOsteoarthritis, HipRegistriesComparatorearly identificationoutlier prosthesisrevisiontotal hip replacement

Identifiers

PMID38087860
PMCPMC11075408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.