Evidence map›Paper›PMID 38087831›Full record

ArticlePalliative medicine2024

Hope and illness expectations: A cross-sectional study in patients with advanced cancer.

Martin Loučka, Andrew D Althouse, Robert M Arnold, Thomas J Smith, Kenneth J Smith, Douglas B White, Margaret Q Rosenzweig, Yael Schenker

Abstract read
In one paragraph

Article in Palliative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Qualitative study on the sense of meaning in life in uremic patients undergoing initial hemodialysis.International journal of qualitative studies on health and well-being · 2025
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin LoučkaThird Faculty of Medicine, Charles University, Prague, Czech Republic.ORCID 0000-0002-9875-7997
Andrew D AlthouseDepartment of Medicine, Center for Research on Health Care Data Center, University of Pittsburgh, Pittsburgh, PA, USA.
Robert M ArnoldSection of Palliative Care and Medical Ethics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Thomas J SmithDivision of General Internal Medicine, Section of Palliative Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kenneth J SmithDivision of General Internal Medicine, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Douglas B WhitePalliative Research Center, University of Pittsburgh and Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Margaret Q RosenzweigPalliative Research Center, University of Pittsburgh and Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Yael SchenkerSection of Palliative Care and Medical Ethics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
A cluster randomized trial of a primary palliative care intervention (CONNECT) for patients with advanced cancerR01CA197103 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHENKER, YAEL · 2016 to 2021
$2.8M
Mentored Patient Oriented Research in Improving Surrogate Decision Making for Patients with Advanced Respiratory FailureK24HL148314 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Douglas B White · 2019 to 2026
$944k
Midcareer Investigator Award in Patient-Oriented Research: Yael Schenker, MD, MASK24AG070285 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHENKER, YAEL · 2021 to 2025
$841k
NCI NIH HHS P30 CA047904NCI NIH HHS R01 CA197103NHLBI NIH HHS K24 HL148314NIA NIH HHS K24 AG070285
6 · The paper itself

Abstract

backgroundThe fear of taking away hope hinders clinicians' willingness to share serious news with patients with advanced disease. Unrealistic illness expectations, on the other hand, can complicate decision making and end-of-life care outcomes. Exploration of the association between hope and illness expectations can support clinicians in better communication with their patients.

aimThe aim of this study was to explore whether realistic illness expectations are associated with reduced hope in people with advanced cancer.

designThis is a cross-sectional secondary analysis of baseline data from a primary palliative care cluster-randomized trial CONNECT (data collected from July 2016 to October 2020). Hope was measured by Herth Hope Index. Illness expectations were measured by assessing patients' understanding of their treatment goals, life expectancy, and terminal illness acknowledgement. Multivariable regression was performed, adjusting for demographical and clinical confounders. SETTING/

participantsAdult patients with advanced solid cancers recruited across 17 oncology clinics.

resultsData from 672 patients were included in the study, with mean age of 69.3 years (±10.2), 53.6% were female. Proportion of patients indicating realistic expectations varied based on which question was asked from 10% to 46%. Median level of hope was 39 (IQR = 36-43). Multivariate non-inferiority regression did not find any significant differences in hope between patients with more and less realistic illness expectations.

conclusionsOur results suggest that hope can be sustained while holding both realistic and unrealistic illness expectations. Communication about serious news should focus on clarifying the expectations as well as supporting people's hopes.

Indexed as

NeoplasmsTerminal CareAdultAgedCross-Sectional StudiesFemaleHopeHumansMaleMiddle AgedMotivationPalliative CareRandomized Controlled Trials as Topicawarenesscancercommunicationcritical illnesshopepalliative carePsycho-oncologyterminally ill

Identifiers

PMID38087831
PMCPMC11552658

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.