Evidence map›Paper›PMID 38087220›Full record

ArticleBMC complementary medicine and therapies2023

Isolation and structure elucidation of the compounds from Teucrium hyrcanicum L. and the investigation of cytotoxicity, antioxidant activity, and protective effect on hydrogen peroxide-induced oxidative stress.

Saeed Ghasemi, Mehdi Evazalipour, Nastaran Peyghanbari, Ehsan Zamani, Peter Bellstedt, Mahan Molaee, Diba Eghbali Koohi, Fatemeh Yousefbeyk

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Saeed GhasemiDepartment of Medicinal Chemistry, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Mehdi EvazalipourDepartment of Pharmaceutical Biotechnology, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Nastaran PeyghanbariDepartment of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Ehsan ZamaniDepartment of Pharmacology and Toxicology, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Peter BellstedtInstitute of Clinical Chemistry, University of Zurich & University Hospital Zurich, Zurich, Switzerland.
Mahan MolaeeDepartment of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Diba Eghbali KoohiDepartment of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
Fatemeh YousefbeykDepartment of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran. yousefbeyk@gums.ac.ir.
Guilan University of Medical Sciences · IRUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTeucrium hyrcanicum L. (family Lamiaceae) is widely distributed in the North and Northwest of Iran. It has been used in the form of tea, tonic, and tincture for the treatment of various diseases such as cough, rheumatism, and fever.

methodsIn this study, the total phenolic and flavonoid contents, antioxidant and cytotoxic activities of methanol extract and different fractions of T. hyrcanicum were measured. Furthermore, the potential ability of T. hyrcanicum to protect against H

resultsThe results indicated that the methanol fraction (MF) had the highest amount of phenolic and flavonoid contents (69.36 mg GAE/g extract and 68.95 mg QE/g extract). The highest radical scavenging activities were observed from MF and ME (IC

conclusionThe isolated compounds (quercetin and acteoside) had significant antioxidant activities and revealed a protective effect on H

Indexed as

Antineoplastic AgentsTeucriumAnimalsAntioxidantsFlavonoidsGlucosidesHydrogen PeroxideMethanolMiceNIH 3T3 CellsOxidative StressPlant ExtractsPolyphenolsQuercetinacteosideAntineoplastic AgentsAntioxidantsFlavonoidsGlucosidesHydrogen PeroxideMethanolPlant ExtractsPolyphenolsQuercetinActeosideAntioxidantCytotoxicityFlavonoidOxidative stressPhenolic compoundsQuercetin

Identifiers

PMID38087220
PMCPMC10714485
OpenAlexW4389623814

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.