Evidence map›Paper›PMID 38087179›Full record

ArticleJournal of general internal medicine2024

Mortality Among Older Medical Patients at Flagship Hospitals and Their Affiliates.

Siddharth Jain, Paul R Rosenbaum, Joseph G Reiter, Omar I Ramadan, Alexander S Hill, Sean Hashemi, Rebecca T Brown, Rachel R Kelz, Lee A Fleisher, Jeffrey H Silber

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Siddharth JainCenter for Outcomes Research, Children's Hospital of Philadelphia, 2716 South Street, Suite 5140, Philadelphia, PA, 19146-2305, USA. sid.jain@yale.edu.ORCID 0000-0001-6122-3775
Paul R RosenbaumThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, PA, USA.
Joseph G ReiterCenter for Outcomes Research, Children's Hospital of Philadelphia, 2716 South Street, Suite 5140, Philadelphia, PA, 19146-2305, USA.
Omar I RamadanThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, PA, USA.
Alexander S HillCenter for Outcomes Research, Children's Hospital of Philadelphia, 2716 South Street, Suite 5140, Philadelphia, PA, 19146-2305, USA.
Sean HashemiCenter for Outcomes Research, Children's Hospital of Philadelphia, 2716 South Street, Suite 5140, Philadelphia, PA, 19146-2305, USA.
Rebecca T BrownThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, PA, USA.
Rachel R KelzThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, PA, USA.
Lee A FleisherThe Leonard Davis Institute of Health Economics, The University of Pennsylvania, Philadelphia, PA, USA.
Jeffrey H SilberCenter for Outcomes Research, Children's Hospital of Philadelphia, 2716 South Street, Suite 5140, Philadelphia, PA, 19146-2305, USA.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · USPhiladelphia VA Medical Center · USUniversity of the Sciences · US

Funding

Postdoctoral Training in Health Services ResearchT32HS026116 · AHRQ · UNIVERSITY OF PENNSYLVANIA · PI GROENEVELD, PETER W., WERNER, RACHEL M · 2018 to 2024
$3.8M
Assessing Hospital Quality of Care for Patients with MultimorbidityR01AG060928 · NIA · CHILDREN'S HOSP OF PHILADELPHIA · PI SILBER, JEFFREY H · 2019 to 2021
$1.5M
AHRQ HHS T32 HS026116NIA NIH HHS R01 AG060928
6 · The paper itself

Abstract

backgroundWe define a "flagship hospital" as the largest academic hospital within a hospital referral region and a "flagship system" as a system that contains a flagship hospital and its affiliates. It is not known if patients admitted to an affiliate hospital, and not to its main flagship hospital, have better outcomes than those admitted to a hospital outside the flagship system but within the same hospital referral region.

objectiveTo compare mortality at flagship hospitals and their affiliates to matched control patients not in the flagship system but within the same hospital referral region.

designA matched cohort study

participantsThe study used hospitalizations for common medical conditions between 2018-2019 among older patients age ≥ 66 years. We analyzed 118,321 matched pairs of Medicare patients admitted with pneumonia (N=57,775), heart failure (N=42,531), or acute myocardial infarction (N=18,015) in 35 flagship hospitals, 124 affiliates, and 793 control hospitals. MAIN MEASURES: 30-day (primary) and 90-day (secondary) all-cause mortality. KEY

results30-day mortality was lower among patients in flagship systems versus control hospitals that are not part of the flagship system but within the same hospital referral region (difference= -0.62%, 95% CI [-0.88%, -0.37%], P<0.001). This difference was smaller in affiliates versus controls (-0.43%, [-0.75%, -0.11%], P=0.008) than in flagship hospitals versus controls (-1.02%, [-1.46%, -0.58%], P<0.001; difference-in-difference -0.59%, [-1.13%, -0.05%], P=0.033). Similar results were found for 90-day mortality. LIMITATIONS: The study used claims-based data.

conclusionsIn aggregate, within a hospital referral region, patients treated at the flagship hospital, at affiliates of the flagship hospital, and in the flagship system as a whole, all had lower mortality rates than matched controls outside the flagship system. However, the mortality advantage was larger for flagship hospitals than for their affiliates.

Indexed as

Hospital MortalityAgedAged, 80 and overCohort StudiesFemaleHeart FailureHospitalizationHospitalsHumansMaleMedicareMyocardial InfarctionPneumoniaUnited StatesaffiliatesAMI.flagship hospitalsheart failurepneumonia

Identifiers

PMID38087179
PMCPMC11074071
OpenAlexW4389627907

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.